Evidence map›Paper›PMID 28235961›Full record

ArticleStroke2017

Distributions of Subclinical Cardiovascular Disease in a Socioeconomically and Racially Diverse Sample.

Carrington R Wendell, Shari R Waldstein, Michele K Evans, Alan B Zonderman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Prospective links between childhood family income and subclinical atherosclerosis in a sample of young men.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Population-Level Gaps in Coronary Artery Disease Care: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
  10. Article
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  14. Article
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  16. Article
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  19. Socioeconomic characteristics of African American women attending community blood pressure screenings.American heart journal plus : cardiology research and practice · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carrington R WendellFrom the Department of Psychology, University of Maryland, Baltimore County (C.R.W., S.R.W.); Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, NIH (C.R.W., M.K.E., A.B.Z.); Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine (S.R.W.); and Geriatric Research Education and Clinical Center, Baltimore VAMC, MD (S.R.W.). crwendell@umbc.edu.
Shari R WaldsteinFrom the Department of Psychology, University of Maryland, Baltimore County (C.R.W., S.R.W.); Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, NIH (C.R.W., M.K.E., A.B.Z.); Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine (S.R.W.); and Geriatric Research Education and Clinical Center, Baltimore VAMC, MD (S.R.W.).
Michele K EvansFrom the Department of Psychology, University of Maryland, Baltimore County (C.R.W., S.R.W.); Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, NIH (C.R.W., M.K.E., A.B.Z.); Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine (S.R.W.); and Geriatric Research Education and Clinical Center, Baltimore VAMC, MD (S.R.W.).
Alan B ZondermanFrom the Department of Psychology, University of Maryland, Baltimore County (C.R.W., S.R.W.); Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, NIH (C.R.W., M.K.E., A.B.Z.); Division of Gerontology & Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine (S.R.W.); and Geriatric Research Education and Clinical Center, Baltimore VAMC, MD (S.R.W.).

Funding

Healthy Aging In Neighborhoods of Diversity Across the Life Span (HANDLS)ZIAAG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2009 to 2025
$70.9M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
HANDLS Scan Substudy: Race, Socioeconomic status, and the BrainR01AG034161 · NIA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI WALDSTEIN, SHARI · 2009 to 2013
$2.8M
NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG034161
6 · The paper itself

Abstract

background and purposeDifferential subgroup vulnerability to subclinical cardiovascular disease is likely, and yet few, if any, studies have addressed interactive relations of age, sex, race, and socioeconomic status (SES) to these conditions to examine nuances of known health disparities. We examined distributions of carotid atherosclerosis and arterial stiffness in a socioeconomically diverse, biracial, urban sample.

methodsParticipants (n=2270) in the population-based HANDLS study (Healthy Aging in Neighborhoods of Diversity Across the Life Span; 30-64 years old, 44% men, 57% African American, 39% with household income <125% federal poverty threshold) underwent carotid intimal medial thickness (IMT) and pulse wave velocity assessment.

resultsIn cross-sectional hierarchical regression analyses, interactive race×SES effects were identified for IMT and pulse wave velocity, such that high SES African Americans had significantly thicker IMTs and faster pulse wave velocities than all other subgroups (ie, low SES African Americans, low SES whites, and high SES whites). A race×sex effect was also identified for IMT, such that the IMT discrepancy between white men and women was more pronounced than the discrepancy between African American men and women. Finally, an SES×sex effect indicated that while IMTs of high SES and low SES men did not significantly differ, high SES women had marginally thicker IMTs than low SES women.

conclusionsHigh SES African Americans may be particularly vulnerable to subclinical cardiovascular diseases, placing them at enhanced risk for clinical cardiovascular diseases, including stroke. These findings suggest that male sex, low SES, and African American ancestry may represent imprecise generalizations as risk factors for subclinical cardiovascular disease.

Indexed as

Carotid Intima-Media ThicknessPulse Wave AnalysisSocial ClassVascular StiffnessAdultBlack or African AmericanCarotid Artery DiseasesCross-Sectional StudiesFemaleHumansMaleMiddle AgedSex FactorsUnited StatesWhite Peoplearterial stiffnessatherosclerosishealth disparitiesintima–media thicknesspulse wave velocitysubclinical cardiovascular disease

Identifiers

PMID28235961
PMCPMC5373954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.