ArticleCirculation2017
Patients With Long-QT Syndrome Caused by Impaired
Registry-linked trialOpen access · hybridAbstract read
In one paragraph
Article in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02775513 (Metabolism of Patients With Genetically Caused Cardiac Arrhythmia), which is not on this map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metabolism of Patients With Genetically Caused Cardiac Arrhythmia
Who cites it
32 citing papers in PubMed, 47 citations in OpenAlex.
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- Effect of hyperglycaemia in combination with moxifloxacin on cardiac repolarization in male and female patients with type I diabetes.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Trial
- Glycaemic outcomes of an Individualized treatMent aPproach for oldER vulnerable patIents: A randomized, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM).Diabetes, obesity & metabolism · 2018Trial
- Long QT syndrome and hypoglycemia in a postbariatric surgery patient with a likely pathogenic variant inJCEM case reports · 2026Article
- Deep single-cell decoding of human pancreatic islets reveals T2D β-cell gene expression defects.The EMBO journal · 2026Article
- Cardiac Manifestations ofHealth science reports · 2026Review
- miR-30d-5p promotes beta cell recovery and immunomodulation in type 1 diabetes.Frontiers in endocrinology · 2026Article
- Voltage-gated potassium channels as important modulators of glucose-stimulated insulin secretion in pancreatic β-cells: insights from rodent and human studies.Frontiers in endocrinology · 2026Review
- From Human to Mouse and Back Again: Genetic and Genomic Ta(i)les of Islet Dysfunction in Type 2 Diabetes.Annual review of genetics · 2025Review
- Low-dose quinine targets KCNH6 to potentiate glucose-induced insulin secretion.Journal of molecular cell biology · 2025Article
- Label-free method to monitor metabolism during long-term culture of human pluripotent stem cell derived cardiomyocytes.Biophotonics discovery · 2025Article
- Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-drivenbioRxiv : the preprint server for biology · 2025Article
- The impact of sulfonylureas on diverse ion channels: an alternative explanation for the antidiabetic actions.Frontiers in cell and developmental biology · 2025Review
- Potassium voltage-gated channel subfamily H member 2 (KCNH2) is a promising target for incretin secretagogue therapies.Signal transduction and targeted therapy · 2024Article
- Evaluation of the lncRNA-miRNA-mRNA ceRNA network in lungs of miR-147Frontiers in pharmacology · 2024Article
- Risk Stratification in People with Diabetes for Fasting During Ramadan: Consensus from Arabic Association for the Study of Diabetes and Metabolism.Current diabetes reviews · 2024Review
- Article
- Relationship Between Index of Cardiac Electrophysiological Balance, Frontal QRS-T Angle and Retinopathy in People with Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Syndromic forms of congenital hyperinsulinism.Frontiers in endocrinology · 2023Review
- Cell-Free Synthesis and Electrophysiological Analysis of Multipass Voltage-Gated Ion Channels Tethered in Microsomal Membranes.Advances in biochemical engineering/biotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 1 country.
Louise Hyltén-CavalliusFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Eva W IepsenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Nicolai J Wewer AlbrechtsenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Mathilde SvendstrupFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Anniek F LubberdingFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Bolette HartmannFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Thomas JespersenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Allan LinnebergFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Michael ChristiansenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Henrik VestergaardFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Oluf PedersenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Jens J HolstFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Jørgen K KantersFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.).
Torben HansenFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.). torekov@sund.ku.dk torben.hansen@sund.ku.dk.
Signe S TorekovFrom Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., A.F.L., B.H., T.J., M.C., J.J.H., J.K.K., S.S.T.); Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (L.H.-C., E.W.I., N.J.W.A., M.S., B.H., H.V., O.P., J.J.H., T.H., S.S.T.); Research Centre for Prevention and Health, the Capital Region of Denmark, Copenhagen (A.L.); Gentofte, Aalborg and Herlev University Hospitals, Denmark (J.K.K.); Faculty of Health Sciences, University of Southern Denmark, Odense (T.H.); Department of Clinical Experimental Research, Rigshospitalet, Denmark (A.L.); Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark (A.L.); Danish Diabetes Academy, Odense, Denmark (E.W.I., M.S.); Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen, Denmark (M.C.); and Steno Diabetes Center Copenhagen, Gentofte, Denmark (H.V.). torekov@sund.ku.dk torben.hansen@sund.ku.dk.
Statens Serum Institut · DKUniversity of Southern Denmark · DKCapital Region of Denmark · DKRigshospitalet · DKUniversity of Copenhagen · DKDanish Diabetes Academy · DK
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLoss-of-function mutations in
methodsEleven patients with LQT2 and 22 sex-, age-, and body mass index-matched control participants underwent a 6-hour 75-g oral glucose tolerance test with ECG recording and blood sampling for measurements of glucose, insulin, C-peptide, glucagon, GLP-1, and GIP.
resultsIn comparison with matched control participants, LQT2 patients had 56% to 78% increased serum insulin, serum C-peptide, plasma GLP-1, and plasma GIP responses (
conclusionsBesides a prolonged cardiac repolarization phase, LQT2 patients display increased GLP-1, GIP, and insulin secretion and defective glucagon secretion, causing decreased plasma glucose and thus increased risk of hypoglycemia. Furthermore, glucose ingestion increased QT interval and aggravated the cardiac repolarization disturbances in LQT2 patients. CLINICAL
trial registrationURL: http://clinicaltrials.gov. Unique identifier: NCT02775513.
Indexed as
MutationAction PotentialsAdultAnimalsBiomarkersBlood GlucoseCase-Control StudiesCell Line, TumorC-PeptideElectrocardiographyERG1 Potassium ChannelFemaleGastric Inhibitory PolypeptideGenetic Predisposition to DiseaseGlucagonGlucagon-Like Peptide 1BiomarkersBlood GlucoseC-PeptideERG1 Potassium ChannelGastric Inhibitory PolypeptideGlucagonGlucagon-Like Peptide 1IncretinsInsulinKCNH2 protein, humanKcnh2 protein, ratPotassium Channel Blockersarrhythmias, cardiacglucagonglucagon-like peptide 1 (GLP-1)glucosehyperglycemiahypoglycemiainsulin-secreting cellslong-QT syndromepotassium channels, voltage-gated
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NCT02775513ClinicalTrials.gov
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