Evidence map›Paper›PMID 28235822›Full record

ArticleDevelopment (Cambridge, England)2017

Transient translational quiescence in primordial germ cells.

Nathalie Oulhen, S Zachary Swartz, Jessica Laird, Alexandra Mascaro, Gary M Wessel

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. METTLing in Stem Cell and Cancer Biology.Stem cell reviews and reports · 2023
    Review
  9. Article
  10. Article
  11. Somatic cell conversion to a germ cell lineage: A violation or a revelation?Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Identification of Translation Start Sites in Bacterial Genomes.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nathalie OulhenDepartment of Molecular and Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
S Zachary SwartzDepartment of Molecular and Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Jessica LairdDepartment of Molecular and Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Alexandra MascaroDepartment of Molecular and Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA.
Gary M WesselDepartment of Molecular and Cell Biology and Biochemistry, Brown University, 185 Meeting Street, Providence, RI 02912, USA gary_wessel@brown.edu.ORCID 0000-0002-1210-9279
Brown University · US

Funding

TRAINING IN MOLECULAR &CELL BIOLOGY &BIOCHEMISTRYT32GM007601 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 1985 to 2019
$6.4M
Post-translational Regulation of Germline DeterminantsR01HD028152 · NICHD · BROWN UNIVERSITY · PI WESSEL, GARY M · 1997 to 2016
$3.9M
NICHD NIH HHS R01 HD028152NIGMS NIH HHS T32 GM007601
6 · The paper itself

Abstract

Stem cells in animals often exhibit a slow cell cycle and/or low transcriptional activity referred to as quiescence. Here, we report that the translational activity in the primordial germ cells (PGCs) of the sea urchin embryo (

Indexed as

Cell CycleProtein BiosynthesisAnimalsBase SequenceBlastulaCRISPR-Cas SystemsGene Expression Regulation, DevelopmentalGerm CellsHydrogen-Ion ConcentrationMitochondriaPeptide Elongation Factor 1RNA-Binding ProteinsRNA, MessengerStrongylocentrotus purpuratusPeptide Elongation Factor 1RNA-Binding ProteinsRNA, MessengerMetabolismPrimordial germ cellsSea urchinTranslation

Identifiers

PMID28235822
PMCPMC5399625
OpenAlexW2590363119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.