Trial reportJournal of the American Heart Association2017
Management and Outcome of Patients With Acute Coronary Syndrome Caused by Plaque Rupture Versus Plaque Erosion: An Intravascular Optical Coherence Tomography Study.
Trial report in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 65 citations in OpenAlex.
- Proprotein Convertase Subtilisin/Kexin Type 9 and Systemic Inflammatory Biomarker Pentraxin 3 for Risk Stratification Among STEMI Patients Undergoing Primary PCI.Journal of inflammation research · 2021Trial
- OFDI-Guided Stentless PCI for Erosion-Related STEMI Unmasking Antiphospholipid Syndrome.JACC. Case reports · 2026Article
- Acute Performance of the DynamX Bioadaptor in Complex Coronary Lesions: An Optical Coherence Tomography-based Evaluation.Interventional cardiology (London, England) · 2026Article
- Optical Coherence Tomography in Acute Coronary Syndromes.Reviews in cardiovascular medicine · 2025Review
- ST-elevation myocardial infarction caused by plaque erosion in a 23-year-old male.Journal of cardiology cases · 2025Article
- Clinical Characteristics and Outcomes of Patients Presenting with Acute Coronary Syndromes and Suspected Plaque Erosion Based on Clinical and Laboratory Criteria.Journal of cardiovascular development and disease · 2025Article
- Uncovering Plaque Erosion: A Distinct Pathway in Acute Coronary Syndromes and a Gateway to Personalized Therapy.Journal of clinical medicine · 2025Review
- The influence between plaque rupture and non-plaque rupture on clinical outcomes in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention: a prospective cohort study.Journal of thoracic disease · 2024Article
- The Impact of Flow-Mediated Vasodilatation on Mechanism and Prognosis in Patients with Acute Coronary Syndrome: A FMD and OCT Study.Reviews in cardiovascular medicine · 2024Article
- Lipid Content Distribution and its Clinical Implication in Patients with Acute Myocardial Infarction-Plaque Erosion: Results from the Prospective OCTAMI Study.Journal of atherosclerosis and thrombosis · 2024Article
- New Concepts on the Pathophysiology of Acute Coronary Syndrome.Reviews in cardiovascular medicine · 2023Review
- Pericoronary Adipose Tissue Radiomics from Coronary Computed Tomography Angiography Identifies Vulnerable Plaques.Bioengineering (Basel, Switzerland) · 2023Article
- Current Toolset in Predicting Acute Coronary Thrombotic Events: The "Vulnerable Plaque" in a "Vulnerable Patient" Concept.Life (Basel, Switzerland) · 2023Review
- Outcomes Following Plaque Erosion-Based Acute Coronary Syndromes Treated Without Stenting: The Plaque Matters.Journal of the American Heart Association · 2022Article
- Prognostic Value of Admission Peak NT-proBNP Combined with Culprit Plaque Types for Predicting Cardiovascular Risk in ST-Segment Elevated Myocardial Infarction: An Optical Coherence Tomography Study.Journal of cardiovascular development and disease · 2022Article
- ST-segment elevation myocardial infarction with plaque erosion, to stent or not to stent: utility of intracoronary optical coherence tomography (OCT) imaging-a case report.European heart journal. Case reports · 2022Article
- Coronary Plaque Erosion Causing STEMI.Journal of community hospital internal medicine perspectives · 2022Article
- Case Report: ST-Elevation Myocardial Infarction Secondary to Acute Atherothrombotic Occlusion Treated With No Stent Strategy.Frontiers in cardiovascular medicine · 2022Article
- Vulnerable Plaque in Patients with Acute Coronary Syndrome: Identification, Importance, and Management.US cardiology · 2022Review
- Culprit lesion characteristics in very young patients with acute coronary syndrome: An optical coherence tomography study.Anatolian journal of cardiology · 2021Observational
Corrections and comments
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Authors and funding
17 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlaque rupture and erosion are the 2 most common mechanisms for acute coronary syndromes. However, the outcome of these 2 distinct pathologies in patients with acute coronary syndromes has never been studied. METHODS AND
resultsWe retrospectively studied 141 patients with acute coronary syndromes who underwent optical coherence tomography (OCT) imaging of the culprit lesion prior to stenting from the Massachusetts General Hospital OCT Registry. Management (stent versus no stent), poststent OCT findings, and outcomes were compared. Among the 141 culprit lesions, rupture was found in 79 (56%) patients and erosion in 62 (44%). Stent implantation was performed in 77 (97.5%) patients with rupture versus 49 (79.0%) in those with erosion (
conclusionsUnfavorable poststent OCT findings were more frequent in rupture patients compared with erosion patients. A subset of erosion patients who were treated conservatively without stenting remained free of adverse cardiac events for up to 1 year.
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