SynthesisNeuroImage2017
Neural correlates of social exclusion across ages: A coordinate-based meta-analysis of functional MRI studies.
Synthesis in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Experimental investigations of social exclusion among adolescents with psychiatric disorders: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Systematic Review and Meta-analysis: Task-based fMRI Studies in Youths With Irritability.Journal of the American Academy of Child and Adolescent Psychiatry · 2023Pooled it
- Neurobiology of loneliness: a systematic review.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Pooled it
- Social exclusion reliably engages the default network: A meta-analysis of Cyberball.NeuroImage · 2021Pooled it
- The vicious circle of social exclusion and psychopathology: a systematic review of experimental ostracism research in psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2020Pooled it
- Brain responses to social punishment: a meta-analysis.Scientific reports · 2019Pooled it
- Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies.Nutrients · 2019Pooled it
- Ostracism, cortisol reactivity, and motivation for high-calorie food in children and adolescents with obesity.International journal of obesity (2005) · 2025Trial
- The role of ventrolateral prefrontal cortex on voluntary emotion regulation of social pain.Human brain mapping · 2023Trial
- The causal role of the bilateral ventrolateral prefrontal cortices on emotion regulation of social feedback.Human brain mapping · 2022Trial
- Domain-specific neural correlates of self-evaluation in relation to sense of acceptance and rejection.Cognitive, affective & behavioral neuroscience · 2026Article
- Heightened Susceptibility to Social Exclusion in Poor Sleepers: A Resting-State fMRI Study.Brain topography · 2026Article
- Neural bias to social feedback moderates link between childhood abuse and subsequent harsh parenting.Social cognitive and affective neuroscience · 2026Article
- Developmental trajectories of head and eye cue integration in gaze perception.Scientific reports · 2026Article
- Identifying neural mediators and cultural moderators of the association between discrimination and depression among Mexican American youth.Scientific reports · 2025Article
- Exposure to Bullying Engages Social Distress Circuits in the Adolescent and Adult Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neural systems for processing social relationship information along two principal dimensions.Communications biology · 2025Article
- Infants' neural processing of emotional faces after ostracism.Scientific reports · 2025Article
- The heart of social pain: examining resting blood pressure and neural sensitivity to exclusion.Social cognitive and affective neuroscience · 2025Article
- Caregiver or Playmate? Fathers' and mothers' brain responses to ball-play with children.Cognitive, affective & behavioral neuroscience · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Given the recent surge in functional neuroimaging studies on social exclusion, the current study employed activation likelihood estimation (ALE) based meta-analyses to identify brain regions that have consistently been implicated across different experimental paradigms used to investigate exclusion. We also examined the neural correlates underlying Cyberball, the most commonly used paradigm to study exclusion, as well as differences in exclusion-related activation between developing (7-18 years of age, from pre-adolescence up to late adolescence) and emerging adult (broadly defined as undergraduates, including late adolescence and young adulthood) samples. Results revealed involvement of the bilateral medial prefrontal and posterior cingulate cortices, right precuneus and left ventrolateral prefrontal cortex across the different paradigms used to examine social exclusion; similar activation patterns were identified when restricting the analysis to Cyberball studies. Investigations into age-related effects revealed that ventrolateral prefrontal activations identified in the full sample were driven by (i.e. present in) developmental samples, while medial prefrontal activations were driven by emerging adult samples. In addition, the right ventral striatum was implicated in exclusion, but only in developmental samples. Subtraction analysis revealed significantly greater activation likelihood in striatal and ventrolateral prefrontal clusters in the developmental samples as compared to emerging adults, though the opposite contrast failed to identify any significant regions. Findings integrate the knowledge accrued from functional neuroimaging studies on social exclusion to date, highlighting involvement of lateral prefrontal regions implicated in regulation and midline structures involved in social cognitive and self-evaluative processes across experimental paradigms and ages, as well as limbic structures in developing samples specifically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.