ArticleGenetics, selection, evolution : GSE2017
TCF21 is related to testis growth and development in broiler chickens.
Article in Genetics, selection, evolution : GSE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Integration of GWAS and transcriptomic analyses reveal candidate genes for duck gonadal development during puberty onset.BMC genomics · 2024Article
- Analysis of the differentially expressed genes in the combs and testes of Qingyuan partridge roosters at different developmental stages.BMC genomics · 2024Article
- Genomic Prediction and Genome-Wide Association Study for Boar Taint Compounds.Animals : an open access journal from MDPI · 2023Article
- Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers.Animals : an open access journal from MDPI · 2022Article
- Genome-wide association studies for growth traits in broilers.BMC genomic data · 2022Article
- Genome-wide detection of CNVs and their association with performance traits in broilers.BMC genomics · 2021Article
- TCF21: a critical transcription factor in health and cancer.Journal of molecular medicine (Berlin, Germany) · 2020Review
- Haplotype-based genome-wide association studies for carcass and growth traits in chicken.Poultry science · 2020Article
- A Novel Regulator of Preadipocyte Differentiation, Transcription Factor TCF21, Functions Partially Through Promoting LPL Expression.Frontiers in physiology · 2019Article
- Genome-wide association for testis weight in the diversity outbred mouse population.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Article
- Identification of genome-wide SNP-SNP interactions associated with important traits in chicken.BMC genomics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLarge amounts of fat deposition often lead to loss of reproductive efficiency in humans and animals. We used broiler chickens as a model species to conduct a two-directional selection for and against abdominal fat over 19 generations, which resulted in a lean and a fat line. Direct selection for abdominal fat content also indirectly resulted in significant differences (P < 0.05) in testis weight (TeW) and in TeW as a percentage of total body weight (TeP) between the lean and fat lines.
resultsA total of 475 individuals from the generation 11 (G
conclusionsThis study revealed that the TCF21 gene is related to testis growth and development in male broilers. This finding will be useful to guide future studies to understand the genetic mechanisms that underlie reproductive efficiency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.