Evidence map›Paper›PMID 28234750›Full record

ReviewCurrent opinion in urology2017

Female urinary microbiota.

Elizabeth R Mueller, Alan J Wolfe, Linda Brubaker

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06573827 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- and Postmenopausal Women

TypeobservationalSponsorUniversity Hospital OstravaRan2024 to 2028Enrolled100ConditionsUrinary Tract InfectionsArmsBlood and urine sample evaluation
NCT06921746 recruitingnot on this mapstarted 2025, after this paper: background citation

Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients

TypeobservationalSponsorUniversity Hospital OstravaRan2025 to 2027Enrolled80ConditionsOveractive BladderArmsUrine Microbiological and Metabolomic Analysis
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 82 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth R MuelleraDepartments of Obstetrics & Gynecology and Urology bDepartment of Microbiology and Immunology, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois, USA.
Alan J Wolfe
Linda Brubaker
Loyola University Chicago · US

Funding

Urinary Incontinence Treatment Network: DCCU01DK058229 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI TENNSTEDT, SHARON L · 2000 to 2012
$16.1M
The Pelvic Floor Disorders NetworkU10HD041250 · NICHD · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA · 2001 to 2015
$3.8M
The Female Urinary Microbiome and Urinary IncontinenceR01DK104718 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, WOLFE, ALAN J · 2016 to 2020
$3.1M
The Female Urinary Microbiome: Adjacent Microbiomes and Clinical AssociationsP20DK108268 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI WOLFE, ALAN J · 2015 to 2016
$583k
Urinary Bacterial Communities in Urge Incontinence WomenR21DK097435 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, GAI, XIAOWU · 2013 to 2014
$414k
The Female Urinary Microbiome and Urinary IncontinenceR56DK104718 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, WOLFE, ALAN J · 2015 to 2015
$300k
NICHD NIH HHS U10 HD041250NIDDK NIH HHS P20 DK108268NIDDK NIH HHS R01 DK104718NIDDK NIH HHS R21 DK097435NIDDK NIH HHS R56 DK104718NIDDK NIH HHS U01 DK058229
6 · The paper itself

Abstract

purpose of reviewThe newly discovered female urinary microbiota has the potential to deepen our understanding of urinary tract health and disease, including common lower urinary tract conditions such as urinary incontinence and urinary tract infection. The spectrum of painful bladder disorders and other less common conditions also may benefit from additional research that includes consideration of the resident bacterial community of the female bladder. The present review provides a clinical context for the rapidly emerging research regarding the female urinary microbiota and its relationships with urinary tract conditions of interest. RECENT

findingsStudies using culture-independent techniques confirm prior reports of bacteria that reside in the female urinary bladder. These resident communities, the female urinary microbiota, possess characteristics that differ between women affected by urgency urinary incontinence and matched, unaffected controls. Enhanced urine culture techniques permit cultivation of organisms, including uropathogens, missed by standard urine culture, but detected by culture-independent sequencing techniques. SUMMARY: New technology is available. Clinical laboratories can modify traditional standard urine culture methods to enhance detection of uropathogens. However, given the existence of the female urinary microbiota, the simple presence of bacteria in the lower urinary tract should not be taken as evidence of infection.

Indexed as

MicrobiotaFemaleHumansUrinalysisUrinary BladderUrinary Bladder DiseasesUrinary IncontinenceUrinary Tract Infections

Identifiers

PMID28234750
PMCPMC5521999
OpenAlexW2590210953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.