Evidence map›Paper›PMID 28233809›Full record

ArticleScientific reports2017

High-Fat Diet Induces Unexpected Fatal Uterine Infections in Mice with aP2-Cre-mediated Deletion of Estrogen Receptor Alpha.

Zsofia Ban, Paul Maurischat, Verena Benz, Sarah Brix, Anna Sonnenburg, Gerhard Schuler, Robert Klopfleisch, Michael Rothe, Jan-Åke Gustafsson, Anna Foryst-Ludwig and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Zsofia BanCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Paul MaurischatCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Verena BenzCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Sarah BrixCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Anna SonnenburgCharité-Universitaetsmedizin Berlin, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany.
Gerhard SchulerClinic for Obstetrics, Gynaecology and Andrology of Large and Small Animals, Faculty of Veterinary Medicine, Justus-Liebig-Universität Gießen, Germany.
Robert KlopfleischDepartment of Veterinary Pathology, College of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Michael RotheLipidomix GmbH, Berlin, Germany.
Jan-Åke GustafssonUniversity of Houston, Center for Nuclear Receptors and Cell Signaling, Houston, TX, USA.
Anna Foryst-LudwigCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Ulrich KintscherCharité-Universitaetsmedizin Berlin, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEFreie Universität Berlin · DEJustus-Liebig-Universität Gießen · DELipidomix (Germany) · DEUniversity of Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen receptor alpha (ERα) is a major regulator of metabolic processes in obesity. In this study we aimed to define the relevance of adipose tissue ERα during high-fat diet (HFD)-induced obesity using female aP2-Cre

Indexed as

Diet, High-FatAdipose TissueAnimalsBacterial InfectionsCells, CulturedEstrogen Receptor alphaFemaleMacrophagesMiceMice, KnockoutPhagocytosisSignal TransductionUterine CervicitisEstrogen Receptor alpha

Identifiers

PMID28233809
PMCPMC5324142
OpenAlexW2590470783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.