ArticlePediatric neurology2017
Endovascular Therapy in Pediatric Stroke: Utilization, Patient Characteristics, and Outcomes.
Article in Pediatric neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Mechanical thrombectomy for pediatric large-vessel occlusion: a systematic review and meta-analysis with post hoc analysis.Neurosurgical review · 2026Pooled it
- Safety of mechanical thrombectomy in pediatric acute ischemic stroke: a systematic review and meta-analysis.Neuroradiology · 2025Pooled it
- Neonatal Thromboembolic Disease: Clinical Spectrum and Emerging Evidence for Diagnostic and Therapeutic Strategies Addressing Unmet Needs.Journal of clinical medicine · 2026Review
- A scoping review of cerebral reperfusion therapies in childhood and adolescence with arterial ischemic stroke.Annals of the Child Neurology Society · 2024Review
- A rare case of pediatric distal middle cerebral artery aneurysm.SAGE open medical case reports · 2024Article
- Traumatic carotid artery injury caused by a metal sipping straw in a pediatric patient: Anesthetic management and considerations.Trauma case reports · 2023Article
- Extended time window mechanical thrombectomy for pediatric acute ischemic stroke.Journal of central nervous system disease · 2022Review
- Acute StrokeTreatment in Children: Are Adult Guidelines Applicable?Current treatment options in neurology · 2022Article
- Pediatric internal carotid artery dissection and stroke after minor head injury.Journal of the American College of Emergency Physicians open · 2021Article
- Endovascular treatment of pediatric ischemic stroke: A single center experience and review of the literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Review
- Primary endovascular treatment for acute ischemic stroke in teenage patients: a short case series.Neuroradiology · 2020Article
- Postintensive Care Syndrome in Pediatric Critical Care Survivors: Therapeutic Options to Improve Outcomes After Acquired Brain Injury.Current treatment options in neurology · 2019Review
- The Burden of Pediatric Neurocritical Care in the United States.Pediatric neurology · 2018Article
- Acute Ischemic Pediatric Stroke Management: An Extended Window for Mechanical Thrombectomy?Frontiers in neurology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
background and purposeDespite strong evidence for endovascular therapy in adults with acute arterial ischemic stroke, limited data exist in children. We aimed to describe endovascular therapy utilization and explore outcomes in a national sample of pediatric arterial ischemic stroke.
methodsWe queried the 2012 Kids' Inpatient Database for children aged greater than 28 days to 20 years with the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for arterial ischemic stroke and evaluated groups based on the procedure code for endovascular therapy. Poor outcome was defined as need for tracheostomy or gastrostomy, discharge to rehabilitation facility, or death. Logistic regression evaluated the association between endovascular therapy and poor outcome, adjusted for age, disease severity (hemiplegia, critical care interventions, neurosurgical interventions), and comorbidities.
resultsWe identified 3184 pediatric discharges with a diagnosis code for arterial ischemic stroke. Thirty-eight (1%) had an endovascular therapy procedure code. Endovascular therapy patients were older (10.2 versus 4.5 years, P < 0.001) and more likely to have hemiplegia/paresis (relative risk [RR] 3.8, 95% confidence interval [CI] 2.0-7.4), aphasia (RR 5.3, 95% CI 2.8-10.1), and facial droop (RR 4.0, 95% CI 1.9-8.7). Endovascular therapy was not associated with critical care and neurosurgical interventions or intracranial hemorrhage. Length of hospitalization, mortality, and discharge disposition were similar between groups. In a multivariable model, endovascular therapy was not associated with poor outcome (adjusted odds ratio 1.7, 95%, CI 0.7-4.1).
conclusionsIn a national sample of children with a diagnosis of arterial ischemic stroke, endovascular therapy was infrequently utilized. Patients with a procedure code for endovascular therapy had significant stroke-related deficits, but outcomes were similar to those in children who did not receive endovascular therapy. Our data, in conjunction with evidence of benefit in adults, support consideration of endovascular therapy for select children with acute stroke.
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Registered trials
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