Evidence map›Paper›PMID 28233641›Full record

ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2017

Guiding transcranial brain stimulation by EEG/MEG to interact with ongoing brain activity and associated functions: A position paper.

Gregor Thut, Til Ole Bergmann, Flavio Fröhlich, Surjo R Soekadar, John-Stuart Brittain, Antoni Valero-Cabré, Alexander T Sack, Carlo Miniussi, Andrea Antal, Hartwig Roman Siebner and 2 more

Open access · greenAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 5 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 5 syntheses or guidelines pooled it, 266 citations in OpenAlex.

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  4. Does non-invasive brain stimulation modulate emotional stress reactivity?Social cognitive and affective neuroscience · 2020
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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 7 countries.

Gregor ThutCentre for Cognitive Neuroimaging, Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK. Electronic address: gregor.thut@glasgow.ac.uk.
Til Ole BergmannDepartment of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, Institute for Medical Psychology and Behavioral Neurobiology, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen, Germany.
Flavio FröhlichDepartment of Psychiatry & Department of Biomedical Engineering & Department of Cell Biology and Physiology & Neuroscience Center & Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Surjo R SoekadarApplied Neurotechnology Lab, Department of Psychiatry and Psychotherapy & MEG Center, University Hospital of Tübingen, Tübingen, Germany.
John-Stuart BrittainNuffield Department of Clinical Neurosciences, Charles Wolfson Neuroscience Clinical Research Facility, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Antoni Valero-CabréCerebral Dynamics, Plasticity and Rehabilitation Group, Frontlab, Institut du Cerveau et la Moelle (ICM), CNRS UMR 7225-INSERM U-117, Université Pierre et Marie Curie, Paris, France.
Alexander T SackDepartment of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Carlo MiniussiCenter for Mind/Brain Sciences CIMeC University of Trento, Rovereto, Italy & Cognitive Neuroscience Section, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Andrea AntalDepartment of Clinical Neurophysiology, University Medical Center, Göttingen, Germany.
Hartwig Roman SiebnerDanish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; Department of Neurology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark.
Ulf ZiemannDepartment of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, University Tübingen, Tübingen, Germany.
Christoph S HerrmannExperimental Psychology Lab, Department of Psychology, Center for Excellence "Hearing4all", European Medical School, Carl von Ossietzky University & Research Center Neurosensory Science, University of Oldenburg, Oldenburg, Germany.
Bispebjerg Hospital · DKCarl von Ossietzky Universität Oldenburg · DECentro San Giovanni di Dio Fatebenefratelli · ITHertie Institute for Clinical Brain Research · DEInstitut du Cerveau · FRJohn Radcliffe Hospital · GBMaastricht University · NLUniversitätsmedizin Göttingen · DEUniversity of North Carolina at Chapel Hill · USUniversity of Tübingen · DEWellcome Centre for Human Neuroimaging · GB

Funding

Rational Optimization of tACS for Targeting Thalamo-Cortical OscillationsR01MH111889 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FROHLICH, FLAVIO · 2016 to 2019
$2.4M
Targeting Cortical Dynamics: Rational Design of Individualized Brain StimulationR01MH101547 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FROHLICH, FLAVIO · 2013 to 2017
$2.2M
EPA EP-C-15-008Medical Research Council MR/N003446/1Medical Research Council MR/N003446/2NIMH NIH HHS R01 MH101547NIMH NIH HHS R01 MH111889Wellcome Trust 098434
6 · The paper itself

Abstract

Non-invasive transcranial brain stimulation (NTBS) techniques have a wide range of applications but also suffer from a number of limitations mainly related to poor specificity of intervention and variable effect size. These limitations motivated recent efforts to focus on the temporal dimension of NTBS with respect to the ongoing brain activity. Temporal patterns of ongoing neuronal activity, in particular brain oscillations and their fluctuations, can be traced with electro- or magnetoencephalography (EEG/MEG), to guide the timing as well as the stimulation settings of NTBS. These novel, online and offline EEG/MEG-guided NTBS-approaches are tailored to specifically interact with the underlying brain activity. Online EEG/MEG has been used to guide the timing of NTBS (i.e., when to stimulate): by taking into account instantaneous phase or power of oscillatory brain activity, NTBS can be aligned to fluctuations in excitability states. Moreover, offline EEG/MEG recordings prior to interventions can inform researchers and clinicians how to stimulate: by frequency-tuning NTBS to the oscillation of interest, intrinsic brain oscillations can be up- or down-regulated. In this paper, we provide an overview of existing approaches and ideas of EEG/MEG-guided interventions, and their promises and caveats. We point out potential future lines of research to address challenges.

Indexed as

BrainElectroencephalographyHumansMagnetoencephalographyTranscranial Direct Current StimulationTranscranial Magnetic StimulationBrain oscillationsElectroencephalographyMagnetoencephalographyNon-invasive transcranial brain stimulation (NTBS)Temporally guided NTBS

Identifiers

PMID28233641
PMCPMC5385293
OpenAlexW2581605628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.