Evidence map›Paper›PMID 28233356›Full record

ArticleAddiction (Abingdon, England)2017

Engagement in HIV care and its correlates among people who inject drugs in St Petersburg, Russian Federation and Kohtla-Järve, Estonia.

Robert Heimer, Nina Usacheva, Russell Barbour, Linda M Niccolai, Anneli Uusküla, Olga S Levina

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Robert HeimerDepartment of the Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Nina UsachevaNGO-Stellit, St Petersburg, Russian Federation.
Russell BarbourDepartment of the Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Linda M NiccolaiDepartment of the Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Anneli UuskülaInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Olga S LevinaNGO-Stellit, St Petersburg, Russian Federation.
Yale University · USSt. Petersburg Department of Steklov Institute of Mathematics · RUUniversity of Tartu · EE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale AITRP Supplement for NicaraguaD43TW001028 · FIC · YALE UNIVERSITY · PI HEIMER, ROBERT · 1998 to 2015
$9.0M
Influences on HIV Prevalence and Service Access among IDUs in Russia and EstoniaR01DA029888 · NIDA · YALE UNIVERSITY · PI HEIMER, ROBERT, UUSKULA, ANNELI · 2010 to 2014
$2.0M
FIC NIH HHS D43 TW001028NCATS NIH HHS UL1 TR001863NIDA NIH HHS R01 DA029888
6 · The paper itself

Abstract

BACKGROUND AND

aimsHIV infection and mortality in Eastern Europe are driven by unsafe injection drug use. We sought to compare engagement in care from HIV testing through receipt of antiretroviral treatment among HIV-positive people who inject drugs (PWID) in St Petersburg, Russian Federation (RF) and Kohtla-Järve, Estonia and identify factors associated significantly with failure to progress at each stage of the HIV treatment cascade.

designCross-sectional biobehavioral surveys of PWID with an analysis stratified by location-two Russian-speaking regions with similar HIV epidemic histories and current prevalence.

settingField-based surveys conducted in St Petersburg, RF and Kohtla-Järve, Estonia.

participantsWe recruited 452 HIV-positive PWID in St Petersburg (November 2012 to June 2013) and 370 HIV-positive PWID in Kohtla-Järve (June-August 2012) using respondent-driven sampling. MEASUREMENTS: Participants were tested for antibodies to HIV, and administered a questionnaire focusing on participants' medical care histories. Engagement in care was categorized as a cascade of five transitional steps through six stages, ranging from HIV testing to current receipt of antiretroviral medications.

findingsProgress along the cascade was greater in Kohtla Järve (32.7% were receiving antiretroviral medications) than in St Petersburg (9.7%). In both locations, we found the steps with high failure rates were the transitions from being aware of one's HIV diagnosis to being in regular care and initiation of highly active antiretroviral therapy (HAART). Factors associated significantly with transition failure in both locations and across steps included high alcohol consumption, variables associated with drug choice and injection frequency and lack of basic medical insurance.

conclusionThe two steps in treatment cascade for HIV-positive PWID in St Petersburg, RF and Kohtla-Järve, Estonia requiring greatest improvement are retention in regular care and initiation of HAART. Both individual behavioral and structural factors are associated with failure to transition along the cascade.

Indexed as

AdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveComorbidityCross-Sectional StudiesEstoniaFemaleHIV InfectionsHumansMalePatient Acceptance of Health CarePrevalenceRussiaSubstance Abuse, IntravenousAnti-HIV AgentsAntiretroviral therapyEastern EuropeHIVHIV testingpeople who inject drugstreatment cascade

Identifiers

PMID28233356
PMCPMC5526080
OpenAlexW2590523709

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.