Evidence map›Paper›PMID 28233339›Full record

ArticleCell biochemistry and function2017

Paracrine effect of CXCR4-overexpressing mesenchymal stem cells on ischemic heart injury.

Shi-Zheng Wu, Ying-Lan Li, Wei Huang, Wen-Feng Cai, Jialiang Liang, Christian Paul, Lin Jiang, Zhi-Chao Wu, Meifeng Xu, Ping Zhu and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell biochemistry and function, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Shi-Zheng WuQinghai Provincial People's Hospital, Xining, Qinghai, China.
Ying-Lan LiQinghai Provincial People's Hospital, Xining, Qinghai, China.
Wei HuangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Wen-Feng CaiDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.ORCID http://orcid.org/0000-0002-1499-4347
Jialiang LiangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Christian PaulDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Lin JiangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Zhi-Chao WuGuangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou, China.
Meifeng XuDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Ping ZhuGuangdong Cardiovascular Institute, Guangdong General Hospital, Guangzhou, China.
Yigang WangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
University of Cincinnati · USGuangdong General Hospital · CNQinghai Provincial Peoples Hospital · CNQinghai University · CN

Funding

Angiomyogenesis With Myoblast Derived iPS CellsR01HL107957 · NHLBI · UNIVERSITY OF CINCINNATI · PI WANG, YIGANG · 2011 to 2015
$3.4M
iPS cells-derived progenitor cells for angiomyogenesisR01HL110740 · NHLBI · UNIVERSITY OF CINCINNATI · PI ASHRAF, MUHAMMAD, WANG, YIGANG · 2011 to 2015
$2.9M
The therapeutic potential of smarter exosomes derived from engineered MSCs on Alzheimer's diseaseR01HL140962 · NHLBI · UNIVERSITY OF CINCINNATI · PI LIU, MIN, XU, MEIFENG · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL107957NHLBI NIH HHS R01 HL110740NHLBI NIH HHS R01 HL140962
6 · The paper itself

Abstract

It has been reported that CXCR4-overexpressing mesenchymal stem cells (MSC

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsAnimals, NewbornCell HypoxiaCulture Media, ConditionedCyclin A2Gene Expression RegulationGenes, ReporterGreen Fluorescent ProteinsMaleMesenchymal Stem CellsMyocardial InfarctionMyocytes, CardiacNeovascularization, PhysiologicParacrine CommunicationPrimary Cell CultureCcna2 protein, ratCulture Media, ConditionedCxcr4 protein, ratCyclin A2enhanced green fluorescent proteinGreen Fluorescent ProteinsReceptors, CXCR4RNA, Small InterferingTransforming Growth Factor beta2Vascular Endothelial Growth Factor Avascular endothelial growth factor A, ratCXCR4 receptormyocardial infarctionproliferationstem cells

Identifiers

PMID28233339
PMCPMC5424893
OpenAlexW2590715302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.