Evidence map›Paper›PMID 28233286›Full record

ArticleAMB Express2017

Thymol and carvacrol induce autolysis, stress, growth inhibition and reduce the biofilm formation by Streptococcus mutans.

Shams Tabrez Khan, Merajuddin Khan, Javed Ahmad, Rizwan Wahab, Omar H Abd-Elkader, Javed Musarrat, Hamad Z Alkhathlan, Abdulaziz A Al-Kedhairy

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Frontiers in oral health · 2026
    Article
  3. Role of Carvacrol in Oral Health: An Overview.Current pharmaceutical design · 2026
    Review
  4. Efficacy ofInternational journal of dentistry · 2026
    Article
  5. Cytotoxic and Antimicrobial Activity of theMolecules (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Natural products in the treatment of diabetic foot infection.European journal of medical research · 2025
    Review
  9. Review
  10. Deletion ofFrontiers in cellular and infection microbiology · 2025
    Article
  11. Inhibitory effects of carvacrol on glucansucrase fromTurkish journal of biology = Turk biyoloji dergisi · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Shams Tabrez KhanZoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. shamsalig75@gmail.com.
Merajuddin KhanDepartment of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Javed AhmadZoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Rizwan WahabZoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Omar H Abd-ElkaderDNA Research Chair, Zoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Javed MusarratDepartment of Ag. Microbiology, Faculty of Agricultural Sciences, AMU, Aligarh, 202002, India.
Hamad Z AlkhathlanDepartment of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia. khathlan@ksu.edu.sa.
Abdulaziz A Al-KedhairyZoology Department, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
King Saud University · SAAligarh Muslim University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organic compounds from plants are an attractive alternative to conventional antimicrobial agents. Therefore, two compounds namely M-1 and M-2 were purified from Origanum vulgare L. and were identified as carvacrol and thymol, respectively. Antimicrobial and antibiofilm activities of these compounds along with chlorhexidine digluconate using various assays was determined against dental caries causing bacteria Streptococcus mutans. The IC

Indexed as

Alternative antimicrobialsCarvacrolOral hygieneS. mutansThymol

Identifiers

PMID28233286
PMCPMC5323333
OpenAlexW2589161411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.