Evidence map›Paper›PMID 28233282›Full record

ArticleProbiotics and antimicrobial proteins2017

Safety of Lactobacillus plantarum ST8Sh and Its Bacteriocin.

Svetoslav Dimitrov Todorov, Luana M Perin, Bruno M Carneiro, Paula Rahal, Wilhelm Holzapfel, Luís Augusto Nero

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Use ofFoods (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Probiotic ofFoods (Basel, Switzerland) · 2022
    Article
  11. Organic Acids Secreted byMolecules (Basel, Switzerland) · 2022
    Article
  12. Article
  13. The Impacts ofMicroorganisms · 2022
    Review
  14. Anti-inflammatory potential of Lactiplantibacillus plantarum IDCC 3501 and its safety evaluation.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  15. Comparison of the Probiotic Potential betweenFoods (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Health-Promoting Role ofMicroorganisms · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Svetoslav Dimitrov TodorovVeterinary Department, Universidade Federal de Viçosa, Campus UFV, Viçosa, Minas Gerais, 36570-900, Brazil. slavi310570@abv.bg.
Luana M PerinVeterinary Department, Universidade Federal de Viçosa, Campus UFV, Viçosa, Minas Gerais, 36570-900, Brazil.
Bruno M CarneiroDepartamento de Engenharia e Tecnologia de Alimentos, UNESP - Universidade Estadual Paulista, Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto, SP, Brazil.
Paula RahalDepartamento de Engenharia e Tecnologia de Alimentos, UNESP - Universidade Estadual Paulista, Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto, SP, Brazil.
Wilhelm HolzapfelGEE, Handong Global University, Pohang, South Korea.
Luís Augusto NeroVeterinary Department, Universidade Federal de Viçosa, Campus UFV, Viçosa, Minas Gerais, 36570-900, Brazil.
Universidade Federal de Viçosa · BRUniversidade Estadual Paulista (Unesp) · BRHandong Global University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total DNA extracted from Lb. plantarum ST8Sh was screened for the presence of more than 50 genes related to production of biogenic amines (histidine decarboxylase, tyrosine decarboxylase, and ornithine decarboxylase), virulence factors (sex pheromones, gelatinase, cytolysin, hyaluronidase, aggregation substance, enterococcal surface protein, endocarditis antigen, adhesion of collagen, integration factors), and antibiotic resistance (vancomycin, tetracycline, erythromycin, gentamicin, chloramphenicol, bacitracin). Lb. plantarum ST8Sh showed a low presence of virulence genes. Only 13 genes were detected (related to sex pheromones, aggregation substance, adhesion of collagen, tetracycline, gentamicin, chloramphenicol, erythromycin, but not to vancomycin, and bacitracin) and may be considered as indication of safety for application in fermented food products. In addition, interaction between Lb. plantarum ST8Sh and drugs from different groups were determined in order to establish possible application of the strain in combination with commercial drugs. Cytotoxicity of the semi-purified bacteriocins produced by Lb. plantarum ST8Sh was depended on applied concentration-highly cytotoxic when applied at 25 μg/mL and no cytotoxicity at 5 μg/mL.

Indexed as

Genes, BacterialBacteriocinsBiogenic AminesCell Line, TumorDNA, BacterialDrug Resistance, Multiple, BacterialEnterococcus faecalisHumansLactiplantibacillus plantarumListeria monocytogenesMicrobial Sensitivity TestsVirulence FactorsBacteriocinsBiogenic AminesDNA, BacterialVirulence FactorsBacteriocinsCytotoxicityLactobacillus plantarumProbioticsSafetyVirulence

Identifiers

PMID28233282
OpenAlexW2589892826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.