ReviewKidney diseases (Basel, Switzerland)2017
Advances in Understanding and Management of Residual Renal Function in Patients with Chronic Kidney Disease.
Review in Kidney diseases (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Rate and reasons for peritoneal dialysis dropout following haemodialysis to peritoneal dialysis switch: a systematic review and meta-analysis.BMC nephrology · 2024Pooled it
- Clinical Value of Metagenomic Next-Generation Sequencing in Early Diagnosis of Peritoneal Dialysis-Associated Peritonitis: A Randomised Controlled Observational Trial.Nephrology (Carlton, Vic.) · 2025Trial
- Impact of Intra-Abdominal Adhesion on Dialysis Outcome in Peritoneal Dialysis Patients.BioMed research international · 2018Trial
- Residual Kidney Function and Response of Left Ventricular Mass to Intensive Hemodialysis: The Frequent Hemodialysis Network Trials.Kidney360 · 2026Article
- Fatigue and Related Sleep Disturbances in Hemodialysis Patients: Prevalence, Associated Factors, and the Influence of Nutritional Status.Nutrients · 2025Article
- Choosing dialysis modality in patients aged 75 and above with end-stage kidney disease: a multicenter cohort study.Scientific reports · 2025Article
- Association Between Residual Kidney Function and Frailty in End-Stage Renal Disease Patients Undergoing Hemodialysis: A Cross-Sectional Study.International journal of nephrology and renovascular disease · 2025Article
- Selection of dialysis methods for end-stage kidney disease patients with diabetes.World journal of diabetes · 2024Review
- Longitudinal Changes in Kidney Solute Clearance in a Prospective Cohort of Patients Initiating Chronic Hemodialysis.Kidney international reports · 2024Article
- Article
- Peritoneal Dialysis for Potential Kidney Transplant Recipients: Pride or Prejudice?Medicina (Kaunas, Lithuania) · 2022Review
- Metabolic Acidosis in Patients with CKD: Epidemiology, Pathogenesis, and Treatment.Kidney diseases (Basel, Switzerland) · 2021Review
- Association of Urinary Dickkopf-3 with Residual Renal Function Decline in Patients Undergoing Peritoneal Dialysis.Medicina (Kaunas, Lithuania) · 2021Article
- Renin Angiotensin Aldosterone System Blockades Does Not Protect Residual Renal Function in Patients with Hemodialysis at 1 Year After Dialysis Initiation: A Prospective Observational Cohort Study.Scientific reports · 2019Observational
- Predicting Residual Function in Hemodialysis and Hemodiafiltration-A Population Kinetic, Decision Analytic Approach.Journal of clinical medicine · 2019Article
- Association between Dyslipidemia and Peritoneal Dialysis Technique Survival.Open access Macedonian journal of medical sciences · 2019Article
- [Effect of dietary sodium intake on residual renal function in patients undergoing peritoneal dialysis: a prospective study of 33 cases].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- Prescribing Hemodialysis or Hemodiafiltration: When One Size Does Not Fit All the Proposal of a Personalized Approach Based on Comorbidity and Nutritional Status.Journal of clinical medicine · 2018Article
- Bone marrow‑derived mesenchymal stem cell‑conditioned medium attenuates tubulointerstitial fibrosis by inhibiting monocyte mobilization in an irreversible model of unilateral ureteral obstruction.Molecular medicine reports · 2018Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResidual renal function (RRF), defined as the ability of native kidneys to eliminate water and uremic toxins, is closely correlated with mortality and morbidity rates among patients receiving either peritoneal dialysis (PD) or hemodialysis (HD) via continuous clearance of middle-sized molecules and protein-bound solutes. Therefore, preserving RRF is considered to be one of the primary goals in managing patients with end-stage renal disease (ESRD). SUMMARY AND KEY MESSAGES: In this article, we provide a review on the understanding and management of RRF in patients on dialysis. RRF may be estimated and measured by calculating the mean 24-hour urine creatinine level and urea clearance. Currently, several middle-sized molecules are reported but rarely used in practice. Many risk factors such as original renal diseases, dietary intake, and nephrotoxic agents impair RRF. Targeting such factors may halt the decline in RRF and offer better outcomes for patients on PD or HD. Except for in PD patients, RRF is a powerful predictor of survival in HD patients. RRF requires more clinical and research attention in the care of patients with ESRD on dialysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.