ReviewKidney diseases (Basel, Switzerland)2017
Disorders of Acid-Base Balance: New Perspectives.
Review in Kidney diseases (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 78 citations in OpenAlex.
- Clinical Implications of Low Anion Gap in Critically Ill Patients: Insights from the BOLD Multi-Centre Blood Gas Dataset.Maedica · 2026Article
- Investigation of Renal Potassium Loss and Anion Gap Patterns in Diabetic Ketoacidosis: A Study From South India.Cureus · 2026Article
- pH-Driven βACS omega · 2026Article
- Chloremia Disturbances in Critical Care: A Narrative Review of Pathophysiology, Clinical Impact and Management Strategies.Life (Basel, Switzerland) · 2026Review
- Rising mortality from electrolyte and acid-base imbalances in the United States (1999-2020): a joinpoint regression analysis of national trends and disparities.Annals of medicine and surgery (2012) · 2026Review
- Predicting the acute pancreatitis severity with multi-machine learning models: constructing an online prediction platform.Frontiers in cellular and infection microbiology · 2026Article
- The health benefits of alkaline water: is it a fact or marketing myth?Frontiers in medicine · 2026Review
- Association of albumin-corrected anion gap with all-cause and cardiovascular mortality in overactive bladder patients.Scientific reports · 2025Article
- Analytical performance evaluation of intelligent quality management of blood gas analyzer.Practical laboratory medicine · 2025Article
- Constructing a prediction model for acute pancreatitis severity based on liquid neural network.Scientific reports · 2025Article
- A second act for spironolactone: cognitive benefits in renal dysfunction - a critical review.Metabolic brain disease · 2025Review
- The impact of sedation and analgesia scores on prognosis in critically ill sepsis patients with sepsis-associated encephalopathy: a retrospective analysis.Frontiers in neurology · 2025Article
- Independent variables of pH: Ten Knights of the Hydrogen Ion Kingdom-Part I. A prospective observational study.PloS one · 2024Observational
- Correlation of serum biochemical parameters and saliva pH in healthy individuals.Saudi journal of biological sciences · 2023Article
- Serum Phosphorus, Serum Bicarbonate, and Renal Function in Relation to Liver CYP1A2 Activity.Diagnostics (Basel, Switzerland) · 2023Article
- Dynamic Modeling of Carbon Dioxide Transport through the Skin Using a Capnometry Wristband.Sensors (Basel, Switzerland) · 2023Article
- The association between albumin corrected anion gap and ICU mortality in acute kidney injury patients requiring continuous renal replacement therapy.Internal and emergency medicine · 2022Article
- Early Blood Analysis and Gas Exchange Monitoring in the Canine Neonate: Effect of Dam's Size and Birth Order.Animals : an open access journal from MDPI · 2022Article
- Article
- Alkalosis-induced hypoventilation in cystic fibrosis: The importance of efficient renal adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisorders of acid-base involve the complex interplay of many organ systems including brain, lungs, kidney, and liver. Compensations for acid-base disturbances within the brain are more complete, while limitations of compensations are more apparent for most systemic disorders. However, some of the limitations on compensations are necessary to survival, in that preservation of oxygenation, energy balance, cognition, electrolyte, and fluid balance are connected mechanistically. SUMMARY: This review aims to give new and comprehensive perspective on understanding acid-base balance and identifying associated disorders. All metabolic acid-base disorders can be approached in the context of the relative losses or gains of electrolytes or a change in the anion gap in body fluids. Acid-base and electrolyte balance are connected not only at the cellular level but also in daily clinical practice. Urine chemistry is essential to understanding electrolyte excretion and renal compensations. KEY MESSAGES: Many constructs are helpful to understand acid-base, but these models are not mutually exclusive. Electroneutrality and the close interconnection between electrolyte and acid-base balance are important concepts to apply in acid-base diagnoses. All models have complexity and shortcuts that can help in practice. There is no reason to dismiss any of the present constructs, and there is benefit in a combined approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.