ReviewSkin appendage disorders2017
Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome.
Review in Skin appendage disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Sexual, physical, and overall adverse effects in patients treated with 5α-reductase inhibitors: a systematic review and meta-analysis.Asian journal of andrologyPooled it
- Risks Associated with 5α-Reductase Inhibitor Use: Analysis of Adverse Drug Reactions Reported to EudraVigilance.Pharmaceuticals (Basel, Switzerland) · 2026Article
- The combination of water extracts ofNutrition research and practice · 2025Article
- Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients.Translational andrology and urology · 2022Article
- Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Sulfotransferase SULT1A1 activity in hair follicle, a prognostic marker of response to the minoxidil treatment in patients with androgenetic alopecia: a review.Postepy dermatologii i alergologii · 2022Review
- How to Deal with the Issues of Fertility, Malignancies, and the Postfinasteride Syndrome while Prescribing Finasteride for Male Pattern Hair Loss.Skin appendage disorders · 2022Article
- Psychiatric Comorbidity Related to the Therapy of Male Androgenetic Alopecia Independent of the 5-Alpha Reductase Pathway.Skin appendage disorders · 2022Article
- Suicidality and Psychological Adverse Events in Patients Treated with Finasteride.Skin appendage disorders · 2021Article
- LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent.Brain sciences · 2021Article
- Understanding Pattern Hair Loss-Hair Biology Impacted by Genes, Androgens, Prostaglandins and Epigenetic Factors.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021Review
- Alterations of gut microbiota composition in post-finasteride patients: a pilot study.Journal of endocrinological investigation · 2021Article
- Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2.Biology · 2021Article
- Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs).Toxicology reports · 2021Review
- Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study.Endocrine connections · 2019Article
- Post-Finasteride Syndrome: An Induced Delusional Disorder with the Potential of a Mass Psychogenic Illness?Skin appendage disorders · 2019Article
- Development of finasteride polymer microspheres for systemic application in androgenic alopecia.International journal of molecular medicine · 2019Article
- [Do benign prostatic hyperplasia drugs affect mood or cognition?]Der Urologe. Ausg. A · 2019Review
- Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?Endocrine · 2018Review
- Post-finasteride syndrome.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postfinasteride syndrome (PFS) is a term recently coined to characterize a constellation of reported undesirable side effects described in postmarketing reports and small uncontrolled studies that developed during or after stopping finasteride treatment, and persisted after drug discontinuation. Symptoms included decreased libido, erectile dysfunction, sexual anhedonia, decreased sperm count, gynecomastia, skin changes, cognitive impairment, fatigue, anxiety, depression, and suicidal ideation. The aim of this study is to review the existing medical literature for evidence-based research of permanent sexual dysfunction and mood changes during treatment with 5-alpha-reductase inhibitors including finasteride and dutasteride.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.