ReviewF1000Research2017
Serotonin receptors in depression: from A to B.
Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 4 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- The Role of the Serotonergic System in Time Perception: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- The 5-HT7 receptor system as a treatment target for mood and anxiety disorders: A systematic review.Journal of psychopharmacology (Oxford, England) · 2023Pooled it
- The serotonin theory of depression: a systematic umbrella review of the evidence.Molecular psychiatry · 2023Pooled it
- Depression and glioblastoma, complicated concomitant diseases: a systemic review of published literature.Neurosurgical review · 2020Pooled it
- Social processing in the amygdala: single-nucleus RNA-sequencing reveals distinct neuronal responses to dominant and subordinate cues.Scientific reports · 2026Article
- The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice.Molecular psychiatry · 2026Article
- Article
- Do sex and gender matter in the pharmacological treatment of depression?Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Enhancing clomipramine antidepressive effect using nanocomplexes via different routes of administration: A comparative study.Iranian journal of basic medical sciences · 2026Article
- Exploring the mechanism of methyl parathion and its degradation product on depression through network toxicology and molecular docking.Scientific reports · 2025Article
- Article
- Gallic acid alleviates omeprazole-induced depressive behavior and memory impairment.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Anxiolytic effect of zinc oxide gallic acid composite nanoparticles following D-galactose administration in rats.Scientific reports · 2025Article
- Time Perception Test in IntelliCage System for Preclinical Study: Linking Depression and Serotonergic Modulation.Diagnostics (Basel, Switzerland) · 2025Article
- A New Augmentation Strategy against Depression Combining SSRIs and the N-terminal Fragment of Galanin (1-15).Current neuropharmacology · 2025Review
- Integrating Molecular Biology and Network Pharmacology to Analyze the Antidepressant Mechanism of Glycyrrhizaglabra.Combinatorial chemistry & high throughput screening · 2025Article
- AnCurrent drug discovery technologies · 2025Article
- Striatal Serotonin Release Signals Reward Value.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Does vitamin D supplementation impact serotonin levels? A systematic review and meta-analysis.Health science reports · 2024Article
- Altered Serotonin 1B Receptor Binding After Escitalopram for Depression Is Correlated With Treatment Effect.The international journal of neuropsychopharmacology · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The role of serotonin in major depressive disorder (MDD) is the focus of accumulating clinical and preclinical research. The results of these studies reflect the complexity of serotonin signaling through many receptors, in a large number of brain regions, and throughout the lifespan. The role of the serotonin transporter in MDD has been highlighted in gene by environment association studies as well as its role as a critical player in the mechanism of the most effective antidepressant treatments - selective serotonin reuptake inhibitors. While the majority of the 15 known receptors for serotonin have been implicated in depression or depressive-like behavior, the serotonin 1A (5-HT
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.