Evidence map›Paper›PMID 28232790›Full record

ArticleFrontiers in molecular neuroscience2017

Cortical Morphogenesis during Embryonic Development Is Regulated by miR-34c and miR-204.

Morten T Venø, Susanne T Venø, Kati Rehberg, Jessy V van Asperen, Bettina H Clausen, Ida E Holm, R Jeroen Pasterkamp, Bente Finsen, Jørgen Kjems

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Morten T VenøDepartment of Molecular Biology and Genetics, Interdisciplinary Nanoscience Center, Aarhus University Aarhus, Denmark.
Susanne T VenøDepartment of Molecular Biology and Genetics, Interdisciplinary Nanoscience Center, Aarhus University Aarhus, Denmark.
Kati RehbergDepartment of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht Utrecht, Netherlands.
Jessy V van AsperenDepartment of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht Utrecht, Netherlands.
Bettina H ClausenNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark Odense, Denmark.
Ida E HolmLaboratory for Experimental Neuropathology, Department of Pathology, Randers Hospital Randers, Denmark.
R Jeroen PasterkampDepartment of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht Utrecht, Netherlands.
Bente FinsenNeurobiology Research, Institute of Molecular Medicine, University of Southern Denmark Odense, Denmark.
Jørgen KjemsDepartment of Molecular Biology and Genetics, Interdisciplinary Nanoscience Center, Aarhus University Aarhus, Denmark.
Aarhus University · DKUniversity Medical Center Utrecht · NLUniversity of Southern Denmark · DKRegional Hospital Randers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The porcine brain closely resembles the human brain in aspects such as development and morphology. Temporal miRNA profiling in the developing embryonic porcine cortex revealed a distinct set of miRNAs, including miR-34c and miR-204, which exhibited a highly specific expression profile across the time of cortical folding. These miRNAs were found to target Doublecortin (DCX), known to be involved in neuron migration during cortical folding of gyrencephalic brains.

Indexed as

brain developmentcortical morphogenesisembryonic developmentmicroRNAmiR-204miR-34cneuronal migration

Identifiers

PMID28232790
PMCPMC5299138
OpenAlexW2586256820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.