Evidence map›Paper›PMID 28232608›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

Metabolic Imaging of Glutamine in Cancer.

Lin Zhu, Karl Ploessl, Rong Zhou, David Mankoff, Hank F Kung

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 83 citations in OpenAlex.

  1. Glutamine metabolism in health and disease.Signal transduction and targeted therapy · 2026
    Review
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  5. Review
  6. Article
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  8. l-[5-Acta pharmaceutica Sinica. B · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. KRAS Mutation Detection with (2Molecular pharmaceutics · 2024
    Article
  15. Review
  16. Review
  17. Monitoring and modelling the glutamine metabolic pathway: a review and future perspectives.Metabolomics : Official journal of the Metabolomic Society · 2023
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lin ZhuCollege of Chemistry 82#, Beijing Normal University, Beijing, China.
Karl PloesslDepartment of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and.
Rong ZhouDepartment of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and.
David MankoffDepartment of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and.
Hank F KungDepartment of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and kunghf@gmail.com.
University of Pennsylvania · USBeijing Normal University · CN

Funding

Novel PET imaging agents for understanding glutamine addiction in cancerR01CA164490 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHODOSH, LEWIS A, KUNG, HANK F · 2011 to 2015
$4.0M
Molecular Imaging Markers for Glutaminolysis in Breast CancerR01CA211337 · NCI · UNIVERSITY OF PENNSYLVANIA · PI MANKOFF, DAVID A., ZHOU, RONG · 2017 to 2021
$2.0M
Metabolic Imaging Marker for Triple Negative Breast CancerR21CA198563 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHOU, RONG · 2015 to 2016
$383k
NCI NIH HHS R01 CA164490NCI NIH HHS R01 CA211337NCI NIH HHS R21 CA198563
6 · The paper itself

Abstract

Glucose and glutamine are the most abundant nutrients for producing energy and building blocks in normal and tumor cells. Increased glycolysis in tumors, the Warburg Effect, is the basis for

Indexed as

GlutamineHumansMolecular ImagingNeoplasmsPositron-Emission TomographyGlutamine18F-(2S,4R)4-fluoroglutamine5-11C-(2S)-glutaminecancer metabolismgliomasglutaminemetabolic imaging

Identifiers

PMID28232608
PMCPMC5373500
OpenAlexW2590313625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.