Evidence map›Paper›PMID 28232234›Full record

ArticleExperimental hematology2017

The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera.

Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Manuela Marra, Orietta Picconi, Agostino Tafuri, Gabriella Girelli, Vladimir N Uversky, Anna Rita Migliaccio

Open access · bronzeAbstract read
In one paragraph

Article in Experimental hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Altered CaCells · 2021
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Mario FalchiNational AIDS Center, Istituto Superiore Sanita, Rome, Italy.
Lilian VarricchioTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fabrizio MartelliHematology/Oncology and Molecular Medicine, Istituto Superiore di Sanità, Roma, Italy.
Manuela MarraHematology/Oncology and Molecular Medicine, Istituto Superiore di Sanità, Roma, Italy.
Orietta PicconiNational AIDS Center, Istituto Superiore Sanita, Rome, Italy.
Agostino TafuriSant'Andrea Hospital-Sapienza, Department of Clinic and Molecular Medicine Sapienza University of Rome, Rome, Italy.
Gabriella GirelliImmunohematology and Transfusion Medicine Unit, Sapienza University of Rome, Rome, Italy.
Vladimir N UverskyDepartment of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; Laboratory of Structural Dynamics, Stability and Folding of Proteins, Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia.
Anna Rita MigliaccioTisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Biomedical and Neuromotorial Sciences, Alma Mater University, Bologna, Italy. Electronic address: annarita.migliaccio@mssm.edu.
Istituto Superiore di Sanità · ITIcahn School of Medicine at Mount Sinai · USSapienza University of Rome · ITUniversity of South Florida · US

Funding

Tissue BankP01CA108671 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Ronald Hoffman · 2006 to 2026
$82.0M
The human glucocorticoid receptor and normal and pathological terminal erythroidR01HL116329 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MIGLIACCIO, ANNA RITA F · 2012 to 2015
$1.7M
NCI NIH HHS P01 CA108671NHLBI NIH HHS R01 HL116329
6 · The paper itself

Abstract

Calreticulin (CALR) is a Ca

Indexed as

ErythropoiesisMutationAmino Acid SubstitutionCalciumCalreticulinCell DifferentiationCell LineCodonErythroblastsErythroid CellsHumansImmunophenotypingJanus Kinase 2Polycythemia VeraProtein TransportReceptors, GlucocorticoidCalciumCalreticulinCodonJanus Kinase 2Receptors, Glucocorticoid

Identifiers

PMID28232234
PMCPMC5779852
OpenAlexW2589858167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.