ArticleEpidemiology and health2017
The impact of disease characteristics on multiple sclerosis patients' quality of life.
Article in Epidemiology and health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Reconsidering Rehabilitation and Lifestyle Approaches to Improve Quality of Life in People with Multiple Sclerosis: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Review
- Sleep disorders in patients with multiple sclerosis.BMC neurology · 2025Article
- Validation of the Arabic Version of the Multiple Sclerosis Impact Scale (MSIS-29): a Rasch Analysis Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Impact of Depression, Fatigue, and Pain on Quality of Life in Slovak Multiple Sclerosis Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Sociodemographic and Clinical Determinants of the Quality of Life of Moroccan People With Multiple Sclerosis.International journal of MS care · 2025Article
- Impact of Socio-Demographic Factors on Quality of Life and Coping Strategies of Children with Different Disabilities.Medicina (Kaunas, Lithuania) · 2024Article
- Perceived health- related quality of life in persons with multiple sclerosis with and without a vascular comorbidity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Predictive Model of Anxiety and Depression Perception in Multiple Sclerosis Patients: Possible Implications for Clinical Treatment.Bioengineering (Basel, Switzerland) · 2024Article
- Validity and reliability of the Persian version of Recce stigma scale in people with multiple sclerosis and its impact on quality of life.BMC neurology · 2024Article
- Neuroprotective Effects of Black Pepper and Its Bioactive Compounds in Age-Related Neurological Disorders.Aging and disease · 2023Review
- Interventions to Improve Quality of Life in Multiple Sclerosis: New Opportunities and Key Talking Points.Degenerative neurological and neuromuscular disease · 2023Review
- Impact of autologous HSCT on the quality of life and fatigue in patients with relapsing multiple sclerosis.Scientific reports · 2022Article
- Perceived facilitators, needs, and barriers to health related quality of life in people with multiple sclerosis: a qualitative investigation.Journal of patient-reported outcomes · 2022Article
- Therapeutic Potential of Combined Therapy of Vitamin A and Vitamin C in the Experimental Autoimmune Encephalomyelitis (EAE) in Lewis Rats.Molecular neurobiology · 2022Article
- Quality of Life in Multiple Sclerosis Patients: Influence of Gender, Age and Marital Status.Materia socio-medica · 2022Article
- Health-Related Quality of Life in people with Multiple Sclerosis: How does this Population Compare to Population-based Norms in Different Health Domains?Journal of patient-reported outcomes · 2022Article
- Analysis of frequency and severity of relapses in multiple sclerosis patients treated with cladribine tablets or placebo: The CLARITY and CLARITY Extension studies.Multiple sclerosis (Houndmills, Basingstoke, England) · 2022Article
- Fatigue, Depression, and Anxiety Among Ambulating Multiple Sclerosis Patients.Frontiers in immunology · 2022Article
- Age, motor dysfunction and neuropsychiatric symptoms impact quality of life in multiple sclerosis.Revista brasileira de enfermagem · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess the quality of life (QoL) of patients with multiple sclerosis (MS), and to investigate the effects of characteristics of MS such as disease course, severity, and relapses on patients' QoL.
methodsThis was a cross-sectional study, in which 171 patients were enrolled. Health-related QoL was assessed using the Persian version of the Multiple Sclerosis Quality of Life-54 questionnaire. To measure patients' disability status, we used the Expanded Disability Status Scale. Other variables included in the study were disease course and relapses of the disease.
resultsThe average scores for patients' physical and mental QoL were 60.9±22.3 and 59.5±21.4, respectively. In a bivariate analysis, disease course, severity of the disease, and relapses were significantly associated with the physical and mental health composite scores. In a hierarchal regression analysis, disease course, severity of the disease, and relapses were responsible for 38 and 16% of the variance in physical and mental QoL, respectively. It was also observed that relapses were a strong predictor of both physical and mental QoL.
conclusionsOur results showed that disease characteristics significantly affected both dimensions of QoL. It is therefore suggested that health care providers should be aware of these characteristics of MS to more successfully improve MS patients' QoL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.