Evidence map›Paper›PMID 28231639›Full record

ReviewWiley interdisciplinary reviews. RNA2017

Cell cycle RNA regulons coordinating early lymphocyte development.

Alison Galloway, Martin Turner

Open access · hybridAbstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. RNA Metabolism in T Lymphocytes.Immune network · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alison GallowayCentre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, UK.
Martin TurnerLaboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, UK.
Babraham Institute · GBUniversity of Dundee · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J00152X/1Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407
6 · The paper itself

Abstract

Lymphocytes undergo dynamic changes in gene expression as they develop from progenitor cells lacking antigen receptors, to mature cells that are prepared to mount immune responses. While transcription factors have established roles in lymphocyte development, they act in concert with post-transcriptional and post-translational regulators to determine the proteome. Furthermore, the post-transcriptional regulation of RNA regulons consisting of mRNAs whose protein products act cooperatively allows RNA binding proteins to exert their effects at multiple points in a pathway. Here, we review recent evidence demonstrating the importance of RNA binding proteins that control the cell cycle in lymphocyte development and discuss the implications for tumorigenesis. WIREs RNA 2017, 8:e1419. doi: 10.1002/wrna.1419 For further resources related to this article, please visit the WIREs website.

Indexed as

AnimalsCell CycleHumansLymphocytesProteomeRNA-Binding ProteinsRNA, MessengerProteomeRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID28231639
PMCPMC5574005
OpenAlexW2591083455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.