Evidence map›Paper›PMID 28231550›Full record

ArticleEnvironmental research2017

Short-term particulate matter exposure induces extracellular vesicle release in overweight subjects.

Matteo Bonzini, Laura Pergoli, Laura Cantone, Mirjam Hoxha, Andrea Spinazzè, Luca Del Buono, Chiara Favero, Michele Carugno, Laura Angelici, Lucia Broggi and 3 more

Abstract read
In one paragraph

Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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  7. Article
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  11. Long- and Short-Term Exposures to PMLife (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Nasal Microbiota Modifies the Effects of Particulate Air Pollution on Plasma Extracellular Vesicles.International journal of environmental research and public health · 2020
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matteo BonziniEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: matteo.bonzini@unimi.it.
Laura PergoliEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Laura CantoneEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Mirjam HoxhaEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Andrea SpinazzèDepartment of Science and High Technology, University of Insubria, Como, Italy.
Luca Del BuonoDepartment of Science and High Technology, University of Insubria, Como, Italy.
Chiara FaveroEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Michele CarugnoEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Laura AngeliciEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Lucia BroggiEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
Andrea CattaneoDepartment of Science and High Technology, University of Insubria, Como, Italy.
Angela C PesatoriEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Valentina BollatiEPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtracellular vesicles (EVs) represent a plausible molecular mechanism linking particulate matter (PM) inhalation to its systemic effects. Microvesicles (MVs) are released from many cell types in response to various stimuli. Increased body mass index (BMI) could modify the response to PM exposure due to enhanced PM uptake and/or an underlying pro-oxidative state. We investigated the relationship between EV release and PM

resultsExposure to PM

conclusionsOur findings emphasize the role of EV release after PM exposure and the susceptibility of overweight subjects. Larger studies with accurate exposure assessment and complete EVs characterization/content analysis, could further clarify the molecular mechanism responsible for PM effects and of hypersusceptibility of overweight subjects.

Indexed as

Extracellular VesiclesAdultAgedAir PollutantsEnvironmental MonitoringFemaleHumansMaleMiddle AgedOverweightParticulate MatterAir PollutantsParticulate MatterAir pollution susceptibilityFlow cytometryMicrovesiclesOverweightPM exposure

Identifiers

PMID28231550
PMCPMC5380126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.