Evidence map›Paper›PMID 28231518›Full record

ArticleJournal of critical care2017

Early bronchoalveolar lavage for intubated trauma patients with TBI or chest trauma.

Tyler J Loftus, Stephen J Lemon, Linda L Nguyen, Stacy A Voils, Scott C Brakenridge, Janeen R Jordan, Chasen A Croft, R Stephen Smith, Frederick A Moore, Philip A Efron and 1 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tyler J LoftusDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Tyler.Loftus@surgery.ufl.edu.
Stephen J LemonDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: lemosj@shands.ufl.edu.
Linda L NguyenDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: linda.nguyen@ufl.edu.
Stacy A VoilsDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: svoils@cop.ufl.edu.
Scott C BrakenridgeDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Scott.Brakenridge@surgery.ufl.edu.
Janeen R JordanDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Janeen.Jordan@surgery.ufl.edu.
Chasen A CroftDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Chasen.Croft@surgery.ufl.edu.
R Stephen SmithDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Steve.Smith@surgery.ufl.edu.
Frederick A MooreDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Frederick.Moore@surgery.ufl.edu.
Philip A EfronDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Philip.Efron@surgery.ufl.edu.
Alicia M MohrDepartment of Surgery and Center for Sepsis and Critical Illness Research, University of Florida College of Medicine, Gainesville, FL 32610. Electronic address: Alicia.Mohr@surgery.ufl.edu.
University of Florida · USFlorida College · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
PICS: A New Horizon for Surgical Critical CareP50GM111152 · NIGMS · UNIVERSITY OF FLORIDA · PI MOORE, FREDERICK A · 2014 to 2018
$10.7M
Molecular Biology in Burns and TraumaT32GM008721 · NIGMS · UNIVERSITY OF FLORIDA · PI Philip A Efron · 1999 to 2026
$5.0M
Chronic Stress and Anemia Recovery following Major TraumaR01GM105893 · NIGMS · UNIVERSITY OF FLORIDA · PI MOHR, ALICIA M · 2013 to 2021
$3.5M
Hematopoietic Stem Cell Dysfunction in the Elderly after Severe InjuryR01GM113945 · NIGMS · UNIVERSITY OF FLORIDA · PI EFRON, PHILIP A · 2015 to 2019
$1.6M
NIA NIH HHS P30 AG028740NIGMS NIH HHS P50 GM111152NIGMS NIH HHS R01 GM105893NIGMS NIH HHS R01 GM113945NIGMS NIH HHS T32 GM008721
6 · The paper itself

Abstract

purposeTo evaluate the efficacy of an early bronchoalveolar lavage (E-BAL) protocol. BAL was performed within 48 h for intubated patients with traumatic brain injury or chest trauma. We hypothesized that E-BAL would decrease antibiotic use and improve outcomes compared to late BAL (L-BAL) triggered by clinical signs of pneumonia.

methodsRetrospective cohort analysis of 132 patients with quantitative BAL and ≥1 risk factor: head Abbreviated Injury Score ≥2, ≥3 rib fractures, or radiographic signs of aspiration or pulmonary contusion. E-BAL (n=71) was compared to L-BAL (n=61). Pneumonia was defined as ≥10

resultsThere were no significant differences in age, injury severity, initial Pao

conclusionsMore than half of all E-BAL patients had pneumonia present early after admission. E-BAL was associated with fewer days on antibiotics and better outcomes than L-BAL.

Indexed as

AdultAnti-Bacterial AgentsBronchoalveolar LavageFemaleHumansIntensive Care UnitsLength of StayLung InjuryMaleMiddle AgedPneumoniaRetrospective StudiesThoracic InjuriesAnti-Bacterial AgentsAntibioticsAspirationBronchoalveolar lavageClinical pulmonary infection scorePneumoniaTrauma

Identifiers

PMID28231518
PMCPMC5401803
OpenAlexW2587784074

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.