ArticlePloS one2017
Interplay between fungicides and parasites: Tebuconazole, but not copper, suppresses infection in a Daphnia-Metschnikowia experimental model.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 17 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural populations are commonly exposed to complex stress scenarios, including anthropogenic contamination and their biological enemies (e.g., parasites). The study of the pollutant-parasite interplay is especially important, given the need for adequate regulations to promote improved ecosystem protection. In this study, a host-parasite model system (Daphnia spp. and the microparasitic yeast Metschnikowia bicuspidata) was used to explore the reciprocal effects of contamination by common agrochemical fungicides (copper sulphate and tebuconazole) and parasite challenge. We conducted 21-day life history experiments with two host clones exposed to copper (0.00, 25.0, 28.8 and 33.1 μg L-1) or tebuconazole (0.00, 154, 192 and 240 μg L-1), in the absence or presence of the parasite. For each contaminant, the experimental design consisted of 2 Daphnia clones × 4 contaminant concentrations × 2 parasite treatments × 20 replicates = 320 experimental units. Copper and tebuconazole decreased Daphnia survival or reproduction, respectively, whilst the parasite strongly reduced host survival. Most importantly, while copper and parasite effects were mostly independent, tebuconazole suppressed infection. In a follow-up experiment, we tested the effect of a lower range of tebuconazole concentrations (0.00, 6.25, 12.5, 25.0, 50.0 and 100 μg L-1) crossed with increasing parasite challenge (2 Daphnia clones × 6 contaminant concentrations × 2 parasite levels × 20 replicates = 480 experimental units). Suppression of infection was confirmed at environmentally relevant concentrations (> 6.25 μg L-1), irrespective of the numbers of parasite challenge. The ecological consequences of such a suppression of infection include interferences in host population dynamics and diversity, as well as community structure and energy flow across the food web, which could upscale to ecosystem level given the important role of parasites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.