Trial reportPloS one2017
Early skin-to-skin contact after cesarean section: A randomized clinical pilot study.
Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study: Sectio Bonding/Early Skin-to-skin Contact (SSC) After Caesarean Section
Delayed Cord Clamping and Early Skin-to-skin Contact in Cesarean Section as Interventions That Promote Exclusive Breastfeeding
Skin-to-Skin Contact With a Sling in Primipar Mothers Who Delivered by Cesarean Section
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Immediate or early skin-to-skin contact for mothers and their healthy newborn infants.The Cochrane database of systematic reviews · 2025Pooled it
- PROSPECT guideline for elective caesarean section: updated systematic review and procedure-specific postoperative pain management recommendations.Anaesthesia · 2021Guideline
- Effect of Skin-To-Skin Contact During Caesarean Section on Pain and Stress in Newborns: A Randomized Controlled Trial.Nursing open · 2026Trial
- Association of duration of skin-to-skin contact after cesarean delivery in China: a superiority, multicentric randomized controlled trial.American journal of obstetrics & gynecology MFM · 2023Trial
- Does immediate skin-to-skin contact at caesarean sections promote uterine contraction and recovery of the maternal blood haemoglobin levels? A randomized clinical trial.Nursing open · 2023Trial
- Barriers and Facilitators to Skin-to-Skin Contact After Caesarean Section: A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- Beyond Pain Management: Skin-to-Skin Contact as a Humanization Strategy in Cesarean Delivery: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- The Effect of the COVID-19 Pandemic and the Establishment of a Ronald McDonald House on Skin-to-Skin Times in the Neonatal Intensive Care Unit: A Retrospective Study.Children (Basel, Switzerland) · 2025Article
- Effects of mother-infant skin-to-skin contact on mother-infant relationship and maternal psychology feelings: A qualitative study.Nursing open · 2024Article
- Elements that influenced immediate mother-neonate contact during the golden hour.Revista da Escola de Enfermagem da U S P · 2022Observational
- The role of the public and private health sectors on factors associated with early essential newborn care practices among institutional deliveries in Ghana.BMC health services research · 2021Article
- Healthy Birth Practice #6: Keep Mother and Newborn Together-It's Best for Mother, Newborn, and Breastfeeding.The Journal of perinatal education · 2019Article
- A Review of Selected Studies That Determine the Physical and Chemical Properties of Saliva in the Field of Dental Treatment.BioMed research international · 2018Review
- The Effect of Breast Massage Training on Self-Efficacy and Perceived Stress of Prim Parous Women: A Clinical Trial Study.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEarly bonding by skin-to-skin contact (SSC) has been demonstrated to be beneficial for mothers and newborns following vaginal delivery. The aim of this study was to investigate the impact of intraoperative bonding (early SSC) after cesarean section on neonatal adaptation, maternal pain and stress response. STUDY
designThis prospective, randomized-controlled pilot study was performed at a single academic tertiary hospital (Department of Obstetrics and Gynecology, Medical University of Graz, Austria) between September 2013 and January 2014. Women were randomly assigned to intraoperative ("early") SCC (n = 17) versus postoperative ("late") SCC (n = 18). Main variables investigated were neonatal transition (Apgar score, arterial oxygen saturation, heart rate and temperature), maternal pain perception and both maternal and neonatal stress response by measuring the stress biomarkers salivary free cortisol and salivary alpha amylase.
resultsThere was no evidence for differences in parameters reflecting neonatal transition or stress response between the 'Early SSC Group' and the 'Late SSC Group'. Maternal salivary cortisol and alpha-amylase levels as well as maternal wellbeing and pain did not differ between the groups. However, the rise of maternal salivary alpha-amylase directly after delivery was higher in the 'Early SSC Group' compared to the 'Late SSC Group' (p = 0.004).
conclusionsThis study did not reveal significant risks for the newborn in terms of neonatal transition when early SSC is applied in the operating room. Maternal condition and stress marker levels did not differ either, although the rise of maternal salivary alpha-amylase directly after delivery was higher in the 'Early SSC Group' compared to the 'Late SSC Group', which may indicate a stressor sign due to intensive activation of the sympathetic-adreno-medullary-system. This needs to be further evaluated in a larger prospective randomized trial.
trial registrationClinicalTrials.gov NCT01894880.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.