Trial reportPloS one2017
Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.
Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01112709 (Maintaining Resistance Training in Older Prediabetic Adults), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Maintaining Resistance Training in Older Prediabetic Adults: Theoretical Approach
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Cardiorespiratory fitness, muscular strength and risk of type 2 diabetes: a systematic review and meta-analysis.Diabetologia · 2019Pooled it
- Programming and supervision of resistance training leads to positive effects on strength and body composition: results from two randomised trials of community fitness programmes.BMC public health · 2018Trial
- Resistance training is associated with spontaneous changes in aerobic physical activity but not overall diet quality in adults with prediabetes.Physiology & behavior · 2017Trial
- Effects of resistance training and aerobic training on improving the composition of middle-aged adults with obesity in an interventional study.Scientific reports · 2025Article
- North Carolina Healthy Active Living: Describing a Wellness Coaching Program for First-Episode Psychosis Clinics.American journal of lifestyle medicine · 2025Article
- Timing of resistance exercise and cardiometabolic outcomes in adults with prediabetes: a secondary analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Effectiveness and Components of Health Behavior Interventions on Increasing Physical Activity Among Healthy Young and Middle-Aged Adults: A Systematic Review with Meta-Analyses.Behavioral sciences (Basel, Switzerland) · 2024Review
- Evolution of the diagnostic value of "the sugar of the blood": hitting the sweet spot to identify alterations in glucose dynamics.Physiological reviews · 2023Review
- Exercise as a community treatment for obesity and the metabolic disease epidemic.Journal of clinical and translational science · 2023Article
- Association between domain-specific physical activity and diabetes in Korean adults.Scientific reports · 2021Article
- Adapting the "Resist Diabetes" Resistance Training Intervention for Veterans.Translational journal of the American College of Sports Medicine · 2020Article
- Evidence-Based, High-Intensity Exercise and Physical Activity for Compressing Morbidity in Older Adults: A Narrative Review.Innovation in aging · 2019Article
- Resistance Exercise Training as a Primary Countermeasure to Age-Related Chronic Disease.Frontiers in physiology · 2019Review
- TrkB signalling pathway mediates the protective effects of exercise in the diabetic rat retina.The European journal of neuroscience · 2018Article
- COSMIC project: consensus on the objectives of the metabolic syndrome in clinic.Diabetes, metabolic syndrome and obesity : targets and therapy · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether a social cognitive theory (SCT)-based intervention improves resistance training (RT) maintenance and strength, and reduces prediabetes prevalence. RESEARCH DESIGN AND
methodsSedentary, overweight/obese (BMI: 25-39.9 kg/m2) adults aged 50-69 (N = 170) with prediabetes participated in the 15-month trial. Participants completed a supervised 3-month RT (2×/wk) phase and were randomly assigned (N = 159) to one of two 6-month maintenance conditions: SCT or standard care. Participants continued RT at a self-selected facility. The final 6-month period involved no contact. Assessments occurred at baseline and months 3, 9, and 15. The SCT faded-contact intervention consisted of nine tailored transition (i.e., supervised training to training alone) and nine follow-up sessions. Standard care involved six generic follow-up sessions. Primary outcomes were prevalence of normoglycemia and muscular strength.
resultsThe retention rate was 76%. Four serious adverse events were reported. After 3 months of RT, 34% of participants were no longer prediabetic. This prevalence of normoglycemia was maintained through month 15 (30%), with no group difference. There was an 18% increase in the odds of being normoglycemic for each % increase in fat-free mass. Increases in muscular strength were evident at month 3 and maintained through month 15 (P<0.001), which represented improvements of 21% and 14% for chest and leg press, respectively. Results did not demonstrate a greater reduction in prediabetes prevalence in the SCT condition.
conclusionsResistance training is an effective, maintainable strategy for reducing prediabetes prevalence and increasing muscular strength. Future research which promotes RT initiation and maintenance in clinical and community settings is warranted.
trial registrationClinicalTrials.gov NCT01112709.
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