Evidence map›Paper›PMID 28230974›Full record

ArticleAnalytical chemistry2017

Femtogram Resolution of Iron Content on a Per Cell Basis: Ex Vivo Storage of Human Red Blood Cells Leads to Loss of Hemoglobin.

J J Chalmers, X Jin, A F Palmer, M H Yazer, L Moore, P Amaya, K Park, X Pan, M Zborowski

Abstract read
In one paragraph

Article in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. A Subpopulation of Monocytes in Normal Human Blood Has Significant Magnetic Susceptibility: Quantification and Potential Implications.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

J J ChalmersWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University , 320 Koffolt Laboratories, 151 West Woodruff Avenue, Columbus, Ohio 43210, United States.ORCID 0000-0003-1723-9774
X JinWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University , 320 Koffolt Laboratories, 151 West Woodruff Avenue, Columbus, Ohio 43210, United States.
A F PalmerWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University , 320 Koffolt Laboratories, 151 West Woodruff Avenue, Columbus, Ohio 43210, United States.
M H YazerDepartment of Pathology, University of Pittsburgh , 3636 Boulevard of the Allies, Pittsburgh, Pennsylvania 15213, United States.
L MooreDepartment of Biomedical Engineering, Cleveland Clinic , 9500 Euclid Avenue, Cleveland, Ohio 44195, United States.
P AmayaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University , 320 Koffolt Laboratories, 151 West Woodruff Avenue, Columbus, Ohio 43210, United States.
K ParkWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University , 320 Koffolt Laboratories, 151 West Woodruff Avenue, Columbus, Ohio 43210, United States.
X PanCenter for Biostatics, The Ohio State University , 310 H Lincoln Tower, 1800 Cannon Drive, Columbus, Ohio 43210, United States.
M ZborowskiDepartment of Biomedical Engineering, Cleveland Clinic , 9500 Euclid Avenue, Cleveland, Ohio 44195, United States.
The Ohio State University · USCleveland Clinic · USUniversity of Pittsburgh · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Magnetophoretic Cell Sorting and AnalysisR01CA062349 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI ZBOROWSKI, MACIEJ · 1994 to 2015
$5.5M
PEGylated megahemoglobin for use as a red blood cell substituteR01HL138116 · NHLBI · OHIO STATE UNIVERSITY · PI CABRALES, PEDRO, KAUMAYA, PRAVIN T. P. · 2017 to 2020
$2.9M
Fractionation of Aged RBCs Based on Hemoglobin ContentR01HL131720 · NHLBI · OHIO STATE UNIVERSITY · PI CHALMERS, JEFFREY JOHN, PALMER, ANDRE FRANCIS · 2017 to 2020
$2.7M
Attenuating the Oxidative and Myocardial Side-Effects of Acellular HemoglobinR01HL126945 · NHLBI · OHIO STATE UNIVERSITY · PI CABRALES, PEDRO, PALMER, ANDRE FRANCIS · 2016 to 2019
$1.7M
Polymerized Hemoglobins for Facilitated Oxygen Transport in Hepatic BioreactorsR01EB021926 · NIBIB · OHIO STATE UNIVERSITY · PI BERTHIAUME, FRANCOIS, PALMER, ANDRE FRANCIS · 2016 to 2019
$1.4M
NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA062349NHLBI NIH HHS R01 HL126945NHLBI NIH HHS R01 HL131720NHLBI NIH HHS R01 HL138116NIBIB NIH HHS R01 EB021926
6 · The paper itself

Abstract

The magnetic characteristics of hemoglobin (Hb) changes with the binding of dioxygen (O

Indexed as

Cell TrackingErythrocytesHemoglobinsHumansIronOxygenRheologyHemoglobinsIronOxygen

Identifiers

PMID28230974
PMCPMC5685515
OpenAlexW2590622639

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.