Evidence map›Paper›PMID 28230788›Full record

ArticleInternational journal of molecular sciences2017

The Adverse Effects of Triptolide on the Reproductive System of Caenorhabditis elegans: Oogenesis Impairment and Decreased Oocyte Quality.

Qinli Ruan, Yun Xu, Rui Xu, Jiaying Wang, Yongqing Hua, Meng Wang, Jinao Duan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qinli RuanCenter for Drug Safety Evaluation and Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. ruanql@njucm.edu.cn.
Yun XuCenter for Drug Safety Evaluation and Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. nzyxuyun@gmail.com.
Rui XuCenter for Drug Safety Evaluation and Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. xurui@njucm.edu.cn.
Jiaying WangCenter for Drug Safety Evaluation and Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. wangjy@njucm.edu.cn.
Yongqing HuaJiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China. hua_yq@njucm.edu.cn.
Meng WangCenter for Drug Safety Evaluation and Research, Nanjing University of Chinese Medicine, Nanjing 210023, China. wangm@njucm.edu.cn.
Jinao DuanJiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China. dja@njucm.edu.cn.
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have revealed that Triptolide damages female reproductive capacity, but the mechanism is unclear. In this study, we used

Indexed as

AnimalsAntispermatogenic AgentsApoptosisCaenorhabditis elegansDiterpenesEpoxy CompoundsFemaleGene Expression RegulationMaleMitosisOocytesOogenesisPhenanthrenesReproductionAntispermatogenic AgentsDiterpenesEpoxy CompoundsPhenanthrenestriptolideapoptosisCaenorhabditis elegansmitosisoogenesisTriptolide

Identifiers

PMID28230788
PMCPMC5343997
OpenAlexW2590609582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.