Evidence map›Paper›PMID 28230785›Full record

ArticleInternational journal of molecular sciences2017

The Application of a Modified d-ROMs Test for Measurement of Oxidative Stress and Oxidized High-Density Lipoprotein.

Fumiaki Ito, Tomoyuki Ito, Chinatsu Suzuki, Tomoyo Yahata, Kazuyuki Ikeda, Kenji Hamaoka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fumiaki ItoInstitute of Health Sciences, Sunstar Inc., Osaka 569-1195, Japan. fumiaki.ito@jp.sunstar.com.
Tomoyuki ItoDepartment of Rehabilitation Medicine, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. rinito@par.odn.ne.jp.
Chinatsu SuzukiDepartment of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. suzuki@koto.kpu-m.ac.jp.
Tomoyo YahataDepartment of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. tomoyo@koto.kpu-m.ac.jp.
Kazuyuki IkedaDepartment of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. ikeda@koto.kpu-m.ac.jp.
Kenji HamaokaDepartment of Pediatric Cardiology and Nephrology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. khamaoka@koto.kpu-m.ac.jp.
Kyoto Prefectural University of Medicine · JPSunstar (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) are involved in the initiation and progression of atherosclerosis. ROS-derived hydroperoxides, as an indicator of ROS production, have been measured by using the diacron reactive oxygen metabolites (d-ROMs) test, which requires iron-containing transferrin in the reaction mixture. In this study we developed a modified d-ROMs test, termed the Fe-ROMs test, where iron ions were exogenously added to the reaction mixture. This modification is expected to exclude the assay variation that comes from different blood iron levels in individuals. In addition, this Fe-ROMs test was helpful for determining the class of plasma lipoproteins that are hydroperoxidized. Low-density lipoprotein/very low-density lipoprotein (LDL/VLDL) and high-density lipoprotein (HDL) were purified by use of an LDL/VLDL purification kit and the dextran sulfate-Mg

Indexed as

Oxidation-ReductionOxidative StressAtherosclerosisBiomarkersEnzyme-Linked Immunosorbent AssayHumansHydrogen PeroxideLipoproteins, HDLLipoproteins, LDLLipoproteins, VLDLMacromolecular SubstancesMetabolomicsMolecular WeightReactive Oxygen SpeciesBiomarkersHydrogen PeroxideLipoproteins, HDLLipoproteins, LDLLipoproteins, VLDLMacromolecular SubstancesReactive Oxygen Speciesatherosclerosisdiacron-reactive oxygen metabolites (d-ROMs) testhigh-density lipoprotein (HDL)oxidative stressoxidized high-density lipoproteinreactive oxygen species (ROS)

Identifiers

PMID28230785
PMCPMC5343988
OpenAlexW2589132636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.