Evidence map›Paper›PMID 28230784›Full record

Trial reportNutrients2017

The Effects of Moderate Whole Grain Consumption on Fasting Glucose and Lipids, Gastrointestinal Symptoms, and Microbiota.

Danielle N Cooper, Mary E Kable, Maria L Marco, Angela De Leon, Bret Rust, Julita E Baker, William Horn, Dustin Burnett, Nancy L Keim

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01403857 (Evaluating Liking, Acceptability and Health Benefits of Grain Products), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01403857 nacompletednot on this map

Evaluating Liking, Acceptability and Health Benefits of Grain Products

TypeinterventionalSponsorUSDA, Western Human Nutrition Research CenterRan2010 to 2013Enrolled45ConditionsFood PreferencesArmsWhole grain foods, Refined grains
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danielle N CooperDepartment of Nutrition, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. dncooper@ucdavis.edu.
Mary E KableWestern Human Nutrition Research Center, USDA-ARS, 430 West Health Sciences Drive, Davis, CA 95616, USA. Mary.Kable@ars.usda.gov.
Maria L MarcoFood Science and Technology, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. mmarco@ucdavis.edu.
Angela De LeonDepartment of Nutrition, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. adeleon@ucdavis.edu.
Bret RustDepartment of Nutrition, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. brust@ucdavis.edu.
Julita E BakerDepartment of Nutrition, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. jemadejska@ucdavis.edu.
William HornWestern Human Nutrition Research Center, USDA-ARS, 430 West Health Sciences Drive, Davis, CA 95616, USA. William.Horn@ars.usda.gov.
Dustin BurnettWestern Human Nutrition Research Center, USDA-ARS, 430 West Health Sciences Drive, Davis, CA 95616, USA. Dustin.Burnett@ars.usda.gov.
Nancy L KeimDepartment of Nutrition, University of California at Davis, 1 Shields Ave, Davis, CA 95616, USA. Nancy.Keim@ars.usda.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to determine if providing wheat, corn, and rice as whole (WG) or refined grains (RG) under free-living conditions will change parameters of health over a six-week intervention in healthy, habitual non-WG consumers. Measurements of body composition, fecal microbiota, fasting blood glucose, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), and triglycerides were made at baseline and post intervention. Subjects were given adequate servings of either WG or RG products based on their caloric need and asked to keep records of grain consumption, bowel movements, and GI symptoms weekly. After six weeks, subjects repeated baseline testing. Significant decreases in total, LDL, and non-HDL cholesterol were seen after the WG treatments but were not observed in the RG treatment. During Week 6, bowel movement frequency increased with increased WG consumption. No significant differences in microbiota were seen between baseline and post intervention, although, abundance of order

Indexed as

DietFeeding BehaviorGastrointestinal MicrobiomeWhole GrainsAdultBacteriaBlood GlucoseBody CompositionCholesterolDefecationDiarrheaFastingFemaleFood HandlingGastrointestinal DiseasesHumansBlood GlucoseCholesterolLipidsTriglyceridesbowel movement frequencybrown ricefasting blood lipidsfasting glucosegastrointestinal symptomsmaizemicrobiotawhole grainswhole wheat

Identifiers

PMID28230784
PMCPMC5331604

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.