Trial reportNutrients2017
Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during Exercise.
Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Acute Intake of Fructose Increases Arterial Pressure in Humans: A Meta-Analysis and Systematic Review.Nutrients · 2024Pooled it
- Factors that Moderate the Effect of Nitrate Ingestion on Exercise Performance in Adults: A Systematic Review with Meta-Analyses and Meta-Regressions.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Acute effects of intra-training carbohydrate ingestion in CrossFit® trained adults: a randomized, triple-blind, placebo-controlled crossover trial.European journal of applied physiology · 2025Trial
- Fuelled or Fooled? Examining the Evidence and Mechanisms Behind Ultra-High Carbohydrate Intake in Endurance Athletes.Sports medicine (Auckland, N.Z.) · 2026Review
- Glucose but not fructose ingestion improves endurance cycling performance despite similar neuromuscular fatigue at exhaustion.European journal of applied physiology · 2026Article
- Hydration Status, Dietary Habits, and Functional Food Consumption Preferences of Football Athletes: A Cross-Sectional Pilot Study.Nutrients · 2025Article
- Effect of Endurance Exercise Training on Gut Microbiota and ER Stress.International journal of molecular sciences · 2024Article
- Are very high rates of exogenous carbohydrate ingestion (>90 g/hr) sufficient or indeed necessary to run a sub-2hr marathon? An analysis of the model predictions of Lukasiewicz and colleagues.Frontiers in nutrition · 2024Article
- The effect of prolonged interval and continuous exercise in the heat on circulatory markers of intestinal barrier integrity.European journal of applied physiology · 2022Article
- Carbohydrate supplementation: a critical review of recent innovations.European journal of applied physiology · 2021Review
- Fructose co-ingestion to increase carbohydrate availability in athletes.The Journal of physiology · 2019Review
- Heat Adaptation in Military Personnel: Mitigating Risk, Maximizing Performance.Frontiers in physiology · 2019Review
- Role of Functional Beverages on Sport Performance and Recovery.Nutrients · 2018Review
- Article
- Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome.Nutrients · 2017Review
- Glucose Plus Fructose Ingestion for Post-Exercise Recovery-Greater than the Sum of Its Parts?Nutrients · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peak exogenous carbohydrate oxidation rates typically reach ~1 g∙min-1 during exercise when ample glucose or glucose polymers are ingested. Fructose co-ingestion has been shown to further increase exogenous carbohydrate oxidation rates. The purpose of this study was to assess the impact of fructose co-ingestion provided either as a monosaccharide or as part of the disaccharide sucrose on exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists. Ten trained male cyclists (VO2peak: 65 ± 2 mL∙kg-1∙min-1) cycled on four different occasions for 180 min at 50% Wmax during which they consumed a carbohydrate solution providing 1.8 g∙min-1 of glucose (GLU), 1.2 g∙min-1 glucose + 0.6 g∙min-1 fructose (GLU + FRU), 0.6 g∙min-1 glucose + 1.2 g∙min-1 sucrose (GLU + SUC), or water (WAT). Peak exogenous carbohydrate oxidation rates did not differ between GLU + FRU and GLU + SUC (1.40 ± 0.06 vs. 1.29 ± 0.07 g∙min-1, respectively, p = 0.999), but were 46% ± 8% higher when compared to GLU (0.96 ± 0.06 g∙min-1: p < 0.05). In line, exogenous carbohydrate oxidation rates during the latter 120 min of exercise were 46% ± 8% higher in GLU + FRU or GLU + SUC compared with GLU (1.19 ± 0.12, 1.13 ± 0.21, and 0.82 ± 0.16 g∙min-1, respectively, p < 0.05). We conclude that fructose co-ingestion (0.6 g∙min-1) with glucose (1.2 g∙min-1) provided either as a monosaccharide or as sucrose strongly increases exogenous carbohydrate oxidation rates during prolonged exercise in trained cyclists.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.