ReviewBrain sciences2017
Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer's Disease, and Vascular Dementia in Older Adults.
Review in Brain sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Benefits of physical activity on cognitive function in patients with neurocognitive disorders: A systematic review.The Journal of frailty & aging · 2025Pooled it
- Effects of aerobic exercise interventions on cognitive function, sleep quality, and quality of life in older adults with mild cognitive impairment: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Exergaming for dementia and mild cognitive impairment.The Cochrane database of systematic reviews · 2024Pooled it
- Network meta-analysis of comparative efficacy of animal-assisted therapy vs. pet-robot therapy in the management of dementia.Frontiers in aging neuroscience · 2023Pooled it
- Brain function effects of exercise interventions for cognitive decline: a systematic review and meta-analysis.Frontiers in neuroscience · 2023Pooled it
- Effect of physical activity on the risk of frailty: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Evidence of Effect of Aerobic Exercise on Cognitive Intervention in Older Adults With Mild Cognitive Impairment.Frontiers in psychiatry · 2021Pooled it
- Current Evidence of Measurement Properties of Physical Activity Questionnaires for Older Adults: An Updated Systematic Review.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Effects of physical activity and exercise on the cognitive function of patients with Alzheimer disease: a meta-analysis.BMC geriatrics · 2019Pooled it
- Perceptions and Experiences of Women Participating in a Digital Technology-Based Physical Activity Intervention (the mPED Trial): Qualitative Study.JMIR public health and surveillance · 2019Trial
- Dementia And Physical Activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial.BMJ (Clinical research ed.) · 2018Trial
- Association of Physical Activity with Dementia Risk in Cancer Survivors: A Korean Nationwide Cohort Study.Cancer research and treatment · 2026Article
- The association between physical activity and depressive symptoms among Chinese older adults: the chain mediating roles of sleep duration and cognitive function.BMC psychology · 2025Article
- Challenges and experiences in digital health equity: a qualitative exploration of the implementation of the Health Code system in China.International journal for equity in health · 2025Article
- Accelerometer Measurements: A Learning Tool to Help Older Adults Understand the Importance of Soft-Landing Techniques in a Community Walking Class.Sensors (Basel, Switzerland) · 2025Article
- The Effect of Physical Activity on Executive Functions in the Elderly Population: A Systematic Review of Randomized Controlled Trials.Brain sciences · 2025Review
- Association between pace of biological aging and cancer and the modulating role of physical activity: a national cross-sectional study.Clinical epigenetics · 2025Article
- Associations Between Chrono-Nutrition Behaviours and Cognitive Function in Middle-Aged Adults: The NUTRICO Cross-Sectional Cohort Study.Nutrition bulletin · 2025Article
- Physical activity changes during midlife link to brain integrity and amyloid burden.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Observational
- Lifestyle interventions for dementia risk reduction: A review on the role of physical activity and diet in Western and Asian Countries.The journal of prevention of Alzheimer's disease · 2025Review
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Alzheimer's disease, vascular dementia, and mild cognitive impairment. We also provide evidence of PA's role in reducing the risks of these diseases and helping to improve cognitive outcomes in older adults. Finally, we describe some potential mechanisms by which this protective effect occurs, providing guidelines for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.