Evidence map›Paper›PMID 28230729›Full record

ArticleNutrients2017

Catechol Groups Enable Reactive Oxygen Species Scavenging-Mediated Suppression of PKD-NFkappaB-IL-8 Signaling Pathway by Chlorogenic and Caffeic Acids in Human Intestinal Cells.

Hee Soon Shin, Hideo Satsu, Min-Jung Bae, Mamoru Totsuka, Makoto Shimizu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
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  3. Broad-Spectrum Hepatoprotection byFoods (Basel, Switzerland) · 2026
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  11. Inhibitory effects ofIranian journal of basic medical sciences · 2022
    Review
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  19. Review
  20. Light Emission from the FeMolecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Hee Soon ShinDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan. hsshin@kfri.re.kr.
Hideo SatsuDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan. satsu@maebashi-it.ac.jp.
Min-Jung BaeDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan. japanpaper04@gmail.com.
Mamoru TotsukaDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan. atotuka@mail.ecc.u-tokyo.ac.jp.
Makoto ShimizuDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan. ms205346@nodai.ac.jp.
Korea Food Research Institute · KRMaebashi Institute of Technology · JPSeoul National University · KRThe University of Tokyo · JPTokyo University of Agriculture · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorogenic acid (CHA) and caffeic acid (CA) are phenolic compounds found in coffee, which inhibit oxidative stress-induced interleukin (IL)-8 production in intestinal epithelial cells, thereby suppressing serious cellular injury and inflammatory intestinal diseases. Therefore, we investigated the anti-inflammatory mechanism of CHA and CA, both of which inhibited hydrogen peroxide (H₂O₂)-induced

Indexed as

Anti-Inflammatory AgentsAntioxidantsCaco-2 CellsCaffeic AcidsCatecholsChlorogenic AcidHumansHydrogen PeroxideInterleukin-8NF-kappa BOxidative StressPhosphorylationProtein Kinase CReactive Oxygen SpeciesSignal TransductionAnti-Inflammatory AgentsAntioxidantscaffeic acidCaffeic AcidscatecholCatecholsChlorogenic AcidHydrogen PeroxideInterleukin-8NF-kappa BProtein Kinase Cprotein kinase DReactive Oxygen Speciescaffeic acidcatechol groupchlorogenic acidinterleukine-8nuclear factor κBprotein kinase Dreactive oxygen species

Identifiers

PMID28230729
PMCPMC5331596
OpenAlexW2590937578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.