Evidence map›Paper›PMID 28230230›Full record

SynthesisThe Cochrane database of systematic reviews2017

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease.

Joseph Em van Agteren, Khin Hnin, Dion Grosser, Kristin V Carson, Brian J Smith

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Lung volume reduction surgery for diffuse emphysema.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. New bronchoscopic treatment modalities for patients with chronic bronchitis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Patient Preferences for Endobronchial Valve Treatment of Severe Emphysema.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2018
    Article
  15. History of lung volume reduction procedures.Journal of thoracic disease · 2018
    Review
  16. Article
  17. Bronchoscopic lung volume reduction: recent updates.Journal of thoracic disease · 2018
    Review
  18. Bronchoscopic interventions for emphysema: Current status.Lung India : official organ of Indian Chest Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Joseph Em van AgterenBasil Hetzel Institute for Translational Health Research, Woodville, Australia.
Khin HninFlinders University, Adelaide, Australia.
Dion GrosserThe Queen Elizabeth Hospital, Adelaide, Australia.
Kristin V CarsonSchool of Medicine, The University of Adelaide, Adelaide, Australia.
Brian J SmithSchool of Medicine, The University of Adelaide, Adelaide, Australia.
University of Adelaide · AUBasil Hetzel Institute · AUFlinders University · AUQueen Elizabeth Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the recent years, a variety of bronchoscopic lung volume reduction (BLVR) procedures have emerged that may provide a treatment option to participants suffering from moderate to severe chronic obstructive pulmonary disease (COPD).

objectivesTo assess the effects of BLVR on the short- and long-term health outcomes in participants with moderate to severe COPD and determine the effectiveness and cost-effectiveness of each individual technique. SEARCH

methodsStudies were identified from the Cochrane Airways Group Specialised Register (CAGR) and by handsearching of respiratory journals and meeting abstracts. All searches are current until 07 December 2016. SELECTION CRITERIA: We included randomized controlled trials (RCTs). We included studies reported as full text, those published as abstract only and unpublished data, if available. DATA COLLECTION AND ANALYSIS: Two independent review authors assessed studies for inclusion and extracted data. Where possible, data from more than one study were combined in a meta-analysis using RevMan 5 software. MAIN

resultsAeriSealOne RCT of 95 participants found that AeriSeal compared to control led to a significant median improvement in forced expiratory volume in one second (FEV AUTHORS'

conclusionsResults for selected BLVR procedures indicate they can provide significant and clinically meaningful short-term (up to one year) improvements in health outcomes, but this was at the expense of increased adverse events. The currently available evidence is not sufficient to assess the effect of BLVR procedures on mortality. These findings are limited by the lack of long-term follow-up data, limited availability of cost-effectiveness data, significant heterogeneity in results, presence of skew and high CIs, and the open-label character of a number of the studies.

Indexed as

BronchiBronchoscopyHumansPneumonectomyPulmonary Disease, Chronic ObstructiveRandomized Controlled Trials as Topic

Identifiers

PMID28230230
PMCPMC6464526
OpenAlexW2470964385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.