Evidence map›Paper›PMID 28229456›Full record

ArticleJournal of the American Geriatrics Society2017

Body Mass Index, Waist Circumference, and Mortality in a Large Multiethnic Postmenopausal Cohort-Results from the Women's Health Initiative.

Zhao Chen, Yann C Klimentidis, Jennifer W Bea, Kacey C Ernst, Chengcheng Hu, Rebecca Jackson, Cynthia A Thomson

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Weight and Body Mass Index in Old Age: Do They Still Matter?Journal of the American Geriatrics Society · 2017
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhao ChenMel and Enid Zuckerman College of Public Health, Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona.
Yann C KlimentidisMel and Enid Zuckerman College of Public Health, Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona.
Jennifer W BeaCancer Center, University of Arizona, Tucson, Arizona.
Kacey C ErnstMel and Enid Zuckerman College of Public Health, Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona.
Chengcheng HuMel and Enid Zuckerman College of Public Health, Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona.
Rebecca JacksonCenter for Clinical and Translational Science, Ohio State University, Columbus, Ohio.
Cynthia A ThomsonCancer Center, University of Arizona, Tucson, Arizona.
University of Arizona · USThe Ohio State University · US

Funding

Longitudinal Changes in Hip Geometry and Skeletal MuscleR01AR049411 · NIAMS · UNIVERSITY OF ARIZONA · PI CHEN, ZHAO · 2003 to 2008
$2.0M
NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNIAMS NIH HHS R01 AR049411NIA NIH HHS HHSN271201100004CWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

objectivesTo determine whether the relationship between anthropometric measurements of obesity and mortality varies according to age, race, and ethnicity in older women.

designProspective cohort study of multiethnic postmenopausal women.

settingWomen's Health Initiative (WHI) observational study and clinical trials in 40 clinics.

participantsPostmenopausal women aged 50-79 participating in WHI (N = 161,808). MEASUREMENTS: Baseline height, weight, and waist circumference (WC) were measured, and body mass index (BMI) was calculated based on height and weight. Demographic, health, and lifestyle data from a baseline questionnaire were used as covariates. The outcome was adjudicated death (n = 18,320) during a mean follow-up of 11.4 ± 3.2 years.

resultsHazard ratios (HRs) and 95% confidence intervals (95% CIs) indicated that ethnicity and age modified (P < .01) the relationship between obesity and mortality. Underweight was associated with higher mortality, but overweight or slight obesity was not a risk factor for mortality in most ethnic groups except for Hispanic women in the obesity I category (HR = 1.42, 95% CI = 1.04-1.95). BMI was not or was only weakly associated with mortality in individuals aged 70-79 (HR = 0.90, 95% CI = 0.85-0.95 for overweight; HR = 0.98, 95 CI = 0.92-1.06 for obese I; HR = 1.11, 95% CI = 1.00-1.23 for obese II; HR = 1.08, 95% CI = 0.92-1.26 for obese III). In contrast, higher central obesity measured using WC was consistently associated with higher mortality in all groups.

conclusionUnderweight is a significant risk factor for mortality in older women, and healthy BMI ranges may need to be specific for age, race, and ethnicity. The findings support a consistent relationship between central obesity and mortality.

Indexed as

Body Mass IndexMortalityPostmenopauseWaist CircumferenceAgedEthnicityFemaleHumansLife StyleMiddle AgedProspective StudiesRacial GroupsWomen's Healthbody mass indexminority healthmortalitywaist circumferencewomen

Identifiers

PMID28229456
PMCPMC5569001
OpenAlexW2591176570

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.