Evidence map›Paper›PMID 28229420›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2017

Noninvasive Assessment of Cell Fate and Biology in Transplanted Mesenchymal Stem Cells.

Federico Franchi, Martin Rodriguez-Porcel

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Federico FranchiDivision of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First St. SW, Rochester, 55905, MN, USA.
Martin Rodriguez-PorcelDivision of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First St. SW, Rochester, 55905, MN, USA. rodriguez.m@mayo.edu.
Mayo Clinic · US

Funding

Imaging mitochondrial function of progenitor cells transplanted to the ischemic myocardiumR01HL119795 · NHLBI · MAYO CLINIC ROCHESTER · PI RODRIGUEZ-PORCEL, MARTIN · 2016 to 2020
$3.1M
Role of Oxidative Stress in Stem Cell Differentiation and SurvivalR00HL088048 · NHLBI · MAYO CLINIC ROCHESTER · PI RODRIGUEZ-PORCEL, MARTIN · 2009 to 2011
$747k
NHLBI NIH HHS R00 HL088048NHLBI NIH HHS R01 HL119795
6 · The paper itself

Abstract

Recently, molecular imaging has become a conditio sine qua non for cell-based regenerative medicine. Developments in molecular imaging techniques, such as reporter gene technology, have increasingly enabled the noninvasive assessment of the fate and biology of cells after cardiovascular applications. In this context, bioluminescence imaging is the most commonly used imaging modality in small animal models of preclinical studies. Here, we present a detailed protocol of a reporter gene imaging approach for monitoring the viability and biology of Mesenchymal Stem Cells transplanted in a mouse model of myocardial ischemia reperfusion injury.

Indexed as

Mesenchymal Stem Cell TransplantationMolecular ImagingAnimalsCell TrackingDisease Models, AnimalGene ExpressionGenes, ReporterGenetic VectorsLuminescent MeasurementsMesenchymal Stem CellsMiceMyocardial Reperfusion InjuryRetroviridaeTransduction, GeneticBioluminescenceHeartLuciferaseMolecular imagingMonitoringReporter geneStem cellsTracking

Identifiers

PMID28229420
PMCPMC5589130
OpenAlexW2590033786

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.