SynthesisInternational urology and nephrology2017
Prevalence of frailty in end-stage renal disease: a systematic review and meta-analysis.
Synthesis in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Prevalence of physical frailty and impact on survival in patients with chronic kidney disease: a systematic review and meta-analysis.BMC nephrology · 2023Pooled it
- Associations between frailty, physical performance, and renal biomarkers in older people with advanced chronic kidney disease.European geriatric medicine · 2021Trial
- Digital self-management application for patients undergoing hemodialysis: influences on health awareness and frailty.BMC nephrology · 2026Observational
- A Snapshot View of Sarcopenia and Frailty Status in Kidney Transplant Recipients.Clinical transplantation · 2026Article
- Personalized Hemodialysis Approaches in Frail Older Individuals.Geriatrics (Basel, Switzerland) · 2026Review
- Comprehensive Conservative Management as Rescue Therapy After Haemodialysis Failure: Two Case Reports.Clinics and practice · 2026Article
- Frailty Among Patients With ADPKD.Kidney international reports · 2025Article
- The Prognostic Role of Frailty and Its Recognition With Simple FRAIL and Fried Frailty Questionnaires in Advanced Cancer Patients.Journal of cachexia, sarcopenia and muscle · 2025Article
- Prevalence and risk factors of pre-frailty and frailty in hemodialysis patients in central China.Scientific reports · 2024Article
- Prognostic Value of Hospital Frailty Risk Score and Clinical Outcomes in Critical Limb-Threatening Ischemia and End-Stage Kidney Disease.Journal of the American Heart Association · 2024Article
- Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link With Oxidative Stress, Plasma Cytokine Profiles, and Nuclear DNA Damage.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- The prevalence and characteristics of frailty in cirrhosis patients: a meta-analysis and systematic review.Frontiers in medicine · 2024Article
- Does autoimmune diseases increase the risk of frailty? A Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Frailty and Clinical Outcomes in Patients Treated With Hemodialysis: A Prospective Cohort Study.Kidney medicine · 2023Article
- Use of frailty assessment instruments in nephrology populations: a scoping review.BMC geriatrics · 2023Article
- Frailty and emergency department utilisation in adults with systemic lupus erythematosus ≤65 years of age: an administrative claims data analysis of Medicaid beneficiaries.Lupus science & medicine · 2023Article
- Anesthetic choice for arteriovenous access creation: A National Anesthesia Clinical Outcomes Registry analysis.The journal of vascular access · 2023Article
- Can Nutrition Contribute to a Reduction in Sarcopenia, Frailty, and Comorbidities in a Super-Aged Society?Nutrients · 2023Review
- The Frailty Index and colon cancer: a 2-sample Mendelian-randomization study.Journal of gastrointestinal oncology · 2023Article
- Comparison between FRAIL Scale and Clinical Frailty Scale in predicting hospitalization in hemodialysis patients.Journal of nephrology · 2023Observational
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to perform a systematic review and meta-analysis on prevalence of frailty among patients with end-stage renal disease (ESRD). ESRD is associated with malnutrition, chronic inflammation, acidemia, impaired hormonal changes, and low physical activity, all of which can directly and indirectly contribute to the development of frailty. Coexistence of ESRD and frailty has been shown to increase risks of adverse health outcomes. Given potential reversibility of frailty, it is important to examine frailty status in this high-risk population.
methodsThree databases (EMBASE, Medline, and CINAHL) were systematically searched for studies providing cross-sectional data of prevalence of frailty defined by cardiovascular health study (CHS) criteria among ESRD patients. Meta-analysis calculated pooled prevalence of frailty according to modifications of CHS criteria.
resultsOf 837 studies identified through the systematic review, seven studies were included. Three studies used both objectively measured and self-reported CHS criteria, and two studies each used only either criteria. Pooled prevalence of frailty was 36.8% (five studies: 95% CI = 29.9-44.1%, I
conclusionsMore than one-third of ESRD patients were frail based on the objectively measured CHS criteria, and that prevalence of frailty almost doubled with the CHS criteria substituting self-reported physical function questionnaire score for objective measurements. Given substantial difference in prevalence of frailty depending on the modifications to CHS criteria, this information should be taken into account when evaluating frailty status among ESRD population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.