Evidence map›Paper›PMID 28229285›Full record

ReviewImmunologic research2017

Topics on vitamin D in systemic lupus erythematosus: analysis of evidence and critical literature review.

António Marinho, Mariana Taveira, Carlos Vasconcelos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

António MarinhoUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), U.Porto, 4099-001, Porto, Portugal. antmarinho@hotmail.com.
Mariana TaveiraServiço de Medicina Interna, ULS Matosinhos, Matosinhos, Portugal.
Carlos VasconcelosUMIB, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), U.Porto, 4099-001, Porto, Portugal.
Universidade do Porto · PTInovamais · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiorgan inflammation, linked to the loss of immune tolerance to self-antigens and the production of a diversity of autoantibodies. The phenotype and progression of SLE have been linked to a combination of environmental, genetic, and hormonal factors. One such environmental factor is vitamin D, a vital hormone with well-established effects on mineral metabolism, skeletal health, and effects on cardiovascular system. The purpose of this article is to make the analysis of evidence and literature review of the pleomorphic effects of Vitamin D in SLE. The article is structured in topics of interest based in the authors' opinion and summarizes the evidence of studies and trials of vitamin D in SLE.

Indexed as

Antigen PresentationEpigenesis, GeneticEvidence-Based MedicineGene Expression RegulationGenetic Predisposition to DiseaseHLA AntigensHumansLupus Erythematosus, SystemicPolymorphism, Single NucleotideRandomized Controlled Trials as TopicReceptors, CalcitriolTh17 CellsT-Lymphocytes, RegulatoryTranscriptomeVitamin DHLA AntigensReceptors, CalcitriolVitamin DAntigen-presenting cellsEpigenomeInflammationLupusMajor histocompatibility complex genesRandomized controlled trialsRegulatory T cellsT-helper 17 cellsTranscriptomeVitamin DVitamin D receptor single nucleotide polymorphismsVitamin D response elements

Identifiers

PMID28229285
OpenAlexW2590793503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.