Evidence map›Paper›PMID 28229255›Full record

ArticleBiogerontology2017

Nordic walking training attenuation of oxidative stress in association with a drop in body iron stores in elderly women.

Jakub Kortas, Agnieszka Kuchta, Krzysztof Prusik, Katarzyna Prusik, Ewa Ziemann, Sandra Labudda, Agnieszka Ćwiklińska, Ewa Wieczorek, Maciej Jankowski, Jedrzej Antosiewicz

2 registry-linked trialsAbstract read
In one paragraph

Article in Biogerontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03417700 nacompletednot on this mapstarted 2018, after this paper: background citation

Vitamin D as a Factor Modifying Adaptation to Diverse Forms of Exercise

TypeinterventionalSponsorGdansk University of Physical Education and SportRan2018 to 2020Enrolled100ConditionsVitamin D3 DeficiencyArmsNW training, Placebo, HICT
NCT05965011 nacompletednot on this mapstarted 2022, after this paper: background citation

Walking on 'Four Legs' to Manage Falls and Fear of Falling

TypeinterventionalSponsorDr. Mohammad Auais, PhDRan2022 to 2023Enrolled37ConditionsRisk of FallingArmsExercise training
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  14. Marathon Run-induced Changes in the Erythropoietin-Erythroferrone-Hepcidin Axis are Iron Dependent.International journal of environmental research and public health · 2020
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  15. Review
  16. Effect ofClinical interventions in aging · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jakub KortasDepartment of Recreation and Qualify Tourism, Gdansk University of Physical Education and Sport, Kazimierza Górskiego 1, 80-336, Gdansk, Poland. jakub.kortas@awf.gda.pl.
Agnieszka KuchtaDepartment of Clinical Chemistry, Medical University of Gdansk, Gdansk, Poland.
Krzysztof PrusikDepartment of Recreation and Qualify Tourism, Gdansk University of Physical Education and Sport, Kazimierza Górskiego 1, 80-336, Gdansk, Poland.
Katarzyna PrusikDepartment of Biomedical Basis of Health, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Ewa ZiemannDepartment of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Sandra LabuddaDepartment of Clinical Chemistry, Medical University of Gdansk, Gdansk, Poland.
Agnieszka ĆwiklińskaDepartment of Clinical Chemistry, Medical University of Gdansk, Gdansk, Poland.
Ewa WieczorekDepartment of Clinical Chemistry, Medical University of Gdansk, Gdansk, Poland.
Maciej JankowskiDepartment of Clinical Chemistry, Medical University of Gdansk, Gdansk, Poland.
Jedrzej AntosiewiczDepartment of Biochemistry, Gdansk University of Physical Education and Sport, Gdansk, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excess body iron accumulation and oxidative stress has been associated with ageing. Regular exercise has been shown to reduce oxidative stress and induce some changes in iron metabolism. However, the effects of exercise on both of these parameters have been poorly investigated. In our study, 35 elderly women participated in 12 weeks of Nordic walking (NW) training (three times a week). We demonstrated that the training caused a significant reduction in malondialdehyde advanced oxidation protein products-markers of oxidative stress but had no effects on paraoxonase 1 activity. These changes were associated with the decrease of blood ferritin (99.4 ± 62.7 vs. 81.4 ± 61.7 ng/ml p < 0.05). Measurement of physical fitness revealed that the training caused a significant improvement in performance and a negative correlation between the blood ferritin and endurance test was recorded (r = -0.34, p = 0.03). In addition, a significant correlation between blood ferritin and fasting glucose level was noted. The training induced a rise of HDL cholesterol from 70.8 ± 19.3-75.3 ± 21.1, p < 0.05, whereas other lipid parameters remained unchanged. In conclusion, NW training reduced body iron stores and it was associated with lower oxidative stress and better endurance.

Indexed as

Oxidative StressWalkingAdvanced Oxidation Protein ProductsAgedAge FactorsAgingBiomarkersBlood GlucoseExercise TherapyExercise ToleranceFemaleFerritinsGeriatric AssessmentHealthy AgingHumansIronAdvanced Oxidation Protein ProductsBiomarkersBlood GlucoseFerritinsIronLipidsMalondialdehydeExerciseHealthy lifestyleIron metabolismLipid peroxidationPhysical activity

Identifiers

PMID28229255
PMCPMC5514214

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.