ReviewNeurobiology of stress2017
How age, sex and genotype shape the stress response.
Review in Neurobiology of stress, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 4 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- An Overview of Stress Analysis Based on Physiological Signals: Systematic Review of Open Datasets and Current Trends.Sensors (Basel, Switzerland) · 2025Pooled it
- Are behavioural and inflammatory profiles different according to type of stressor, developmental stage, and sex in rodent models of depression? A systematic review.Molecular psychiatry · 2025Pooled it
- A systematic review and Bayesian network meta-analysis on the efficacy and potential of mobile interventions for stress management.Nature human behaviour · 2025Pooled it
- A Systematic Review of Biological Mechanisms and Chronic Pain Outcomes During Stress Reduction Interventions.Biological research for nursing · 2020Pooled it
- Nomogram for Postoperative Headache in Adult Patients Undergoing Elective Cardiac Surgery.Journal of the American Heart Association · 2022Trial
- Long-term psychobiological stress responses following soft political repression.Scientific reports · 2026Article
- Review
- The temporal dynamics of perceived stress and depression in college students: An ecological momentary assessment.PsyCh journal · 2025Article
- Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study.Child psychiatry and human development · 2025Article
- Effects of the COVID-19 pandemic on the health of medical students transitioning from traditional education to distance learning: a prospective cohort.BMC medical education · 2025Article
- Differential effects of chronic unpredictable stress on behavioral and molecular (cortisol and microglia-related neurotranscriptomic) responses in adult leopard (leo) zebrafish.Fish physiology and biochemistry · 2025Article
- Influence of Early-Life Stress on the Excitability of Dynorphin Neurons in the Adult Mouse Dorsal Horn.The journal of pain · 2024Article
- Sex Differences in the Severity and Progression of Neuropsychiatric Symptoms Across Different Dementia Types.Neurology. Clinical practice · 2024Article
- Gender-related stress factors and emotional perception in migraine: a structured online questionnaire in migraine patients and controls.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Observational
- Exploring the Domestication Syndrome Hypothesis in Dogs: Pigmentation Does Not Predict Cortisol Levels.Animals : an open access journal from MDPI · 2023Article
- Article
- Article
- A comparison of stress reactivity between BTBR and C57BL/6J mice: an impact of early-life stress.Experimental brain research · 2023Article
- Targeting stressor-induced dysfunctions in protein-protein interaction networks via epichaperomes.Trends in pharmacological sciences · 2023Review
- Interplay between stress and cancer-A focus on inflammation.Frontiers in physiology · 2023Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to chronic stress is a leading pre-disposing factor for several neuropsychiatric disorders as it often leads to maladaptive responses. The response to stressful events is heterogeneous, underpinning a wide spectrum of distinct changes amongst stress-exposed individuals'. Several factors can underlie a different perception to stressors and the setting of distinct coping strategies that will lead to individual differences on the susceptibility/resistance to stress. Beyond the factors related to the stressor itself, such as intensity, duration or predictability, there are factors intrinsic to the individuals that are relevant to shape the stress response, such as age, sex and genetics. In this review, we examine the contribution of such intrinsic factors to the modulation of the stress response based on experimental rodent models of response to stress and discuss to what extent that knowledge can be potentially translated to humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.