Evidence map›Paper›PMID 28228929›Full record

ArticleJournal of tissue engineering

Decellularized bone matrix grafts for calvaria regeneration.

Dong Joon Lee, Shannon Diachina, Yan Ting Lee, Lixing Zhao, Rui Zou, Na Tang, Han Han, Xin Chen, Ching-Chang Ko

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 85 citations in OpenAlex.

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  19. Decellularization of Bone Tissue.Advances in experimental medicine and biology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dong Joon LeeOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Shannon DiachinaOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Yan Ting LeeOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Lixing ZhaoOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Rui ZouOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Na TangOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Han HanOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Xin ChenOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
Ching-Chang KoOral and Craniofacial Health Sciences Research, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA; Department of Orthodontics, UNC School of Dentistry, University of North Carolina, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

Engineering novel bio-inspired materials for stem-cell mediated bone regenerationR01DE022816 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KO, CHING-CHANG · 2014 to 2018
$2.0M
NIDCR NIH HHS R01 DE022816
6 · The paper itself

Abstract

Decellularization is a promising new method to prepare natural matrices for tissue regeneration. Successful decellularization has been reported using various tissues including skin, tendon, and cartilage, though studies using hard tissue such as bone are lacking. In this study, we aimed to define the optimal experimental parameters to decellularize natural bone matrix using 0.5% sodium dodecyl sulfate and 0.1% NH

Indexed as

Decellularized bone matrixhistomorphometrymesenchymal stem cellmineral apposition rateorthotopic

Identifiers

PMID28228929
PMCPMC5308431
OpenAlexW2581540547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.