Evidence map›Paper›PMID 28228846›Full record

ArticleEpigenetics & chromatin2017

Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in

Natallia Kalinava, Julie Zhouli Ni, Kimberly Peterman, Esteban Chen, Sam Guoping Gu

Open access · goldAbstract read
In one paragraph

Article in Epigenetics & chromatin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natallia KalinavaDepartment of Molecular Biology and Biochemistry, Rutgers the State University of New Jersey, Piscataway, NJ 08854 USA.
Julie Zhouli NiDepartment of Molecular Biology and Biochemistry, Rutgers the State University of New Jersey, Piscataway, NJ 08854 USA.
Kimberly PetermanDepartment of Molecular Biology and Biochemistry, Rutgers the State University of New Jersey, Piscataway, NJ 08854 USA.
Esteban ChenDepartment of Molecular Biology and Biochemistry, Rutgers the State University of New Jersey, Piscataway, NJ 08854 USA.
Sam Guoping GuDepartment of Molecular Biology and Biochemistry, Rutgers the State University of New Jersey, Piscataway, NJ 08854 USA.
Rutgers, The State University of New Jersey · USNelson Engineering (United States) · US

Funding

RNA-mediated Chromatin Regulation and Epigenetic Inheritance in C. elegansR01GM111752 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI GU, GUOPING · 2014 to 2023
$3.1M
NIGMS NIH HHS R01 GM111752
6 · The paper itself

Abstract

backgroundGermline nuclear RNAi in

resultsHere we demonstrate that siRNA-mediated H3K9me3 requires combined activities of three H3K9 histone methyltransferases: MET-2, SET-25, and SET-32.

conclusionsNuclear RNAi-mediated H3K9me3 in

Indexed as

RNA InterferenceAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsChromatin ImmunoprecipitationGenomeGenomic InstabilityGerm CellsHigh-Throughput Nucleotide SequencingHistone-Lysine N-MethyltransferaseHistone MethyltransferasesHistonesMethylationMicroscopy, FluorescenceMutagenesisCaenorhabditis elegans ProteinsCarrier ProteinsHistone-Lysine N-MethyltransferaseHistone MethyltransferasesHistonesOMA-1 protein, C elegansRNA, Double-StrandedRNA, MessengerRNA, Small Interfering

Identifiers

PMID28228846
PMCPMC5311726
OpenAlexW2588395757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.