ArticleOpen biology2017
A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism.
Article in Open biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- The Biosynthetic Pathway of Mycolic Acids: Dual-Function Targets for Tuberculosis Therapeutics and Green Steroid Drugs Biomanufacturing.Pharmaceutics · 2025Review
- A split ALFA tag-nanobody system for protein localization and proximity proteomics in mycobacteria.mBio · 2025Article
- A proteomic and functional view of intrabacterial lipid inclusion biogenesis in mycobacteria.mBio · 2025Article
- Investigating the role ofMicrobiology spectrum · 2024Article
- Intrabacterial lipid inclusion-associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis.FEBS open bio · 2023Article
- Genetic analysis of acyl-CoA carboxylases involved in lipid accumulation in Rhodococcus jostii RHA1.Applied microbiology and biotechnology · 2023Article
- Pathogenicity and virulence ofVirulence · 2022Review
- MadR mediates acyl CoA-dependent regulation of mycolic acid desaturation in mycobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Mechanisms of Drug-Induced Tolerance in Mycobacterium tuberculosis.Clinical microbiology reviews · 2020Review
- Non-Tuberculous Mycobacteria: Molecular and Physiological Bases of Virulence and Adaptation to Ecological Niches.Microorganisms · 2020Review
- FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence ofFrontiers in microbiology · 2020Article
- Oleiferasaponin A₂, a Novel Saponin fromMolecules (Basel, Switzerland) · 2018Article
- Identification of novel lipid modifications and intermembrane dynamics inJournal of lipid research · 2018Article
- Lipid metabolism and its implication in mycobacteria-host interaction.Current opinion in microbiology · 2018Review
- The Mycobacterial Cell Envelope: A Relict From the Past or the Result of Recent Evolution?Frontiers in microbiology · 2018Article
- Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria.Open biology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Unlike most bacteria, mycobacteria rely on the multi-domain enzyme eukaryote-like fatty acid synthase I (FAS I) to make fatty acids de novo. These metabolites are precursors of the biosynthesis of most of the lipids present both in the complex mycobacteria cell wall and in the storage lipids inside the cell. In order to study the role of the type I FAS system in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.