Evidence map›Paper›PMID 28228424›Full record

Trial reportThe American journal of clinical nutrition2017

Widespread sucralose exposure in a randomized clinical trial in healthy young adults.

Allison C Sylvetsky, Peter J Walter, H Martin Garraffo, Kim Robien, Kristina I Rother

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03972176 (Determination of Perinatal Exposure to Non-caloric Sweeteners. Implications for the Development of Preferences for Sweet Taste, and Weight Gain During the First Year of Life), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03972176 unknown statusnot on this mapstarted 2019, after this paper: background citation

Determination of Perinatal Exposure to Non-caloric Sweeteners. Implications for the Development of Preferences for Sweet Taste, and Weight Gain During the First Year of Life

Typeobservational_patient_registrySponsorUniversity of ChileRan2019 to 2021Enrolled315ConditionsExposures Associated With Pregnancy, Delivery and Lactation
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impacts of non-nutritive sweeteners on the human microbiome.Immunometabolism (Cobham, Surrey) · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Allison C SylvetskyDepartment of Exercise and Nutrition Sciences and the asylvets@gwu.edu.ORCID 0000-0003-0424-2798
Peter J WalterClinical Mass Spectrometry Core and.ORCID 0000-0001-8571-398X
H Martin GarraffoClinical Mass Spectrometry Core and.ORCID 0000-0001-7442-8999
Kim RobienDepartment of Exercise and Nutrition Sciences and the.ORCID 0000-0002-2120-2280
Kristina I RotherSection on Pediatric Diabetes and Metabolism, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD.ORCID 0000-0002-8421-131X
IONICS Mass Spectrometry (Canada) · CAMilken Institute · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNutrition Sciences (Belgium) · BE

Funding

Clinical Stable Isotope Research & SupportZICDK075039 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI WALTER, PETER · 2009 to 2025
$23.2M
Metabolic effects of non-nutritive sweetenersZIADK075093 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI ROTHER, KRISTINA · 2013 to 2019
$2.2M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DietAdolescentAdultCarbonated BeveragesEnergy IntakeEnvironmental ExposureFemaleGastrointestinal MicrobiomeHumansMaleNon-Nutritive SweetenersNutrition SurveysReference ValuesSucroseYoung AdultNon-Nutritive SweetenersSucrosetrichlorosucroseartificial sweetenersdietdiet sodalow-calorie sweetenersnon-nutritive sweetenerssucralose

Identifiers

PMID28228424
PMCPMC5366047
OpenAlexW2590845465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.