Evidence map›Paper›PMID 28228403›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.

Yixin Su, Jianli Bi, Victor M Pulgar, Mark C Chappell, James C Rose

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sex differences in prenatal programming of hypertension by dexamethasone.Experimental biology and medicine (Maywood, N.J.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yixin SuDepartment of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Jianli BiDepartment of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Victor M PulgarDepartment of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, North Carolina; vpulgar@wakehealth.edu.ORCID 0000-0002-0049-9150
Mark C ChappellHypertension and Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, North Carolina.
James C RoseDepartment of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Wake Forest University · US

Funding

The Impact of Antenatal Steroid Exposure on the Intrarenal Renin-Angiotensin SystP01HD047584 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ROSE, JAMES C. · 2005 to 2016
$13.0M
FETAL ENDOCRINE-CARDIOVASCULAR RELATIONSHIPSR01HD017644 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ROSE, JAMES C. · 1985 to 2011
$2.8M
Novel Angiotensin-(1-7) Endopeptidase in Fetal ProgrammingR21HD084227 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, ROSE, JAMES C. · 2016 to 2017
$426k
NICHD NIH HHS P01 HD047584NICHD NIH HHS R01 HD017644NICHD NIH HHS R21 HD084227
6 · The paper itself

Abstract

We previously reported a sex-specific effect of antenatal treatment with betamethasone (Beta) on sodium (Na

Indexed as

Angiotensin IAnimalsBetamethasoneBiological TransportCells, CulturedFemaleGlucocorticoidsKidney Tubules, ProximalMaleNitric OxidePeptide FragmentsPhenotypePrimary Cell CultureProto-Oncogene MasProto-Oncogene ProteinsReceptors, G-Protein-CoupledAngiotensin Iangiotensin I (1-7)BetamethasoneGlucocorticoidsNitric OxidePeptide FragmentsProto-Oncogene MasProto-Oncogene ProteinsReceptors, G-Protein-CoupledSodiumfetal programmingkidneyrenin-angiotensin systemsex differences

Identifiers

PMID28228403
PMCPMC5495882
OpenAlexW2590092235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.