Evidence map›Paper›PMID 28228294›Full record

ReviewIndian heart journal

Cardiac resynchronization therapy in patients with mild heart failure is a reversal therapy.

Sadeq Ali-Hassan-Al-Saegh, Seyed Jalil Mirhosseini, Ali Akbar Karimi-Bondarabadi, Azadeh Sahidzadeh, Parisa Mahdavi, Mahbube Tahernejad, Safieyehsadat Heydari, Alexander Weymann, Mohamed Zeriouh, Anton Sabashnikov and 1 more

Erratum issuedOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Sadeq Ali-Hassan-Al-SaeghCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: S.alihassan.cardiosurg@gmail.com.
Seyed Jalil MirhosseiniCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ali Akbar Karimi-BondarabadiCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Azadeh SahidzadehCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Parisa MahdaviCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mahbube TahernejadCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Safieyehsadat HeydariDepartment of Research and Technology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Alexander WeymannDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Mohamed ZeriouhDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Anton SabashnikovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Aron-Frederik PopovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom.
Shahid Sadoughi University of Medical Sciences and Health Services · IRRoyal Brompton & Harefield NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review with meta-analysis sought to determine the efficacy, safety of implantation of cardiac resynchronization therapy (CRT) in mild heart failure (HF). Medline, Embase, Elsevier, and Sciences online database as well as Google scholar literature were used for selecting appropriate studies with randomized controlled design. The literature search of all major databases retrieved 2035 studies. After screening, a total of 10 trials were identified that reported outcomes of interest. Pooled analysis was performed on left ventricular (LV) ejection fraction (P<0.001), LV end-diastolic volume (P<0.001), LV end-systolic volume (P<0.001), LV end-diastolic diameter (P<0.001), LV end-systolic diameter (P<0.001), incidence of progression of heart failure (P<0.001), mortality (P=0.06), infection (P=0.1), and pneumothorax (P=0.08). Overall, implantation of CRT in patients with asymptomatic and mild HF resulted in improved cardiac function, decreased progression of HF, trend to decrease of mortality in short to long-term follow-up.

Indexed as

Ventricular RemodelingCardiac Resynchronization TherapyDisease ProgressionHeart FailureHumansTreatment OutcomeVentricular Function, LeftCardiac resynchronization therapyHeart failureMildly symptomatic

Identifiers

PMID28228294
PMCPMC5319120
OpenAlexW2509873607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.