Evidence map›Paper›PMID 28228275›Full record

ArticleImmunity2017

RSV Takes Control of Neonatal Breg Cells: Two Hands on the Wheel.

Peter J M Openshaw

Open access · bronzeAbstract readComment
In one paragraph

Article in Immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Peter J M OpenshawRespiratory Sciences, National Heart and Lung Institute, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK. Electronic address: p.openshaw@imperial.ac.uk.
Lung Institute · US

Funding

Department of HealthMedical Research Council G1000758Medical Research Council MR/R502121/1Wellcome Trust 087805Wellcome Trust P57603/4
6 · The paper itself

Abstract

The viral attachment protein of RSV has many surprising features, especially its mimicry of fractalkine (CX3CL1). Zhivaki et al. (2017) now show that, in addition to using this homology to attach to ciliated cells, it activates human neonatal regulatory B cells, thereby inhibiting immunological responses.

Indexed as

B-Lymphocytes, RegulatoryHumans

Identifiers

PMID28228275
PMCPMC7612800
OpenAlexW2590653974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.