Evidence map›Paper›PMID 28228266›Full record

ArticleCell reports2017

Rapid State-Dependent Alteration in K

Matthew J M Rowan, Jason M Christie

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Molecular mechanism governing the plasticity of use-dependent spike broadening in dorsal root ganglion neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Beyond a Transmission Cable-New Technologies to Reveal the Richness in Axonal Electrophysiology.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  11. Article
  12. Article
  13. Regulation of Neurotransmitter Release by KAdvances in neurobiology · 2023
    Article
  14. Review
  15. Biophysical KeLife · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. The potassium channel subunit KProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew J M RowanMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Jason M ChristieMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA. Electronic address: jason.christie@mpfi.org.
Max Planck Florida Institute for Neuroscience · US

Funding

Action Potential Signaling in Axons of CNS InterneuronsR01NS083894 · NINDS · MAX PLANCK FLORIDA CORPORATION · PI CHRISTIE, JASON M · 2013 to 2017
$2.1M
Local control of the action potential in axonsF32NS083127 · NINDS · MAX PLANCK FLORIDA CORPORATION · PI ROWAN, MATTHEW J.M. · 2014 to 2016
$169k
NINDS NIH HHS F32 NS083127NINDS NIH HHS R01 NS083894
6 · The paper itself

Abstract

In many neurons, subthreshold depolarization in the soma can transiently increase action-potential (AP)-evoked neurotransmission via analog-to-digital facilitation. The mechanisms underlying this form of short-term synaptic plasticity are unclear, in part, due to the relative inaccessibility of the axon to direct physiological interrogation. Using voltage imaging and patch-clamp recording from presynaptic boutons of cerebellar stellate interneurons, we observed that depolarizing somatic potentials readily spread into the axon, resulting in AP broadening, increased spike-evoked Ca

Indexed as

Action PotentialsAnimalsAxonsCalciumCerebellumInterneuronsMiceNeuronsPatch-Clamp TechniquesPotassium ChannelsPresynaptic TerminalsProtein Kinase CShaw Potassium ChannelsSignal TransductionSynapsesSynaptic TransmissionCalciumKcnc4 protein, mousePotassium ChannelsProtein Kinase CShaw Potassium Channelsanalog signalingaxonBoutonHCNKv3.4short-term plasticity

Identifiers

PMID28228266
PMCPMC5328503
OpenAlexW2589380375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.